Evidence map›Paper›PMID 41948098›Full record

ArticleJournal of orthopaedics and sports medicine2026

Integrating Mechanical Diagnosis and Therapy Within Multidisciplinary Biopsychosocial Care for Chronic Musculoskeletal Pain.

Manas Aavula, David Parvizi, Sugeeth Kandikattu, Devendra K Agrawal

Abstract read
In one paragraph

Article in Journal of orthopaedics and sports medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Manas AavulaDepartment of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California 91766, USA.
David ParviziDepartment of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California 91766, USA.
Sugeeth KandikattuDepartment of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California 91766, USA.
Devendra K AgrawalDepartment of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California 91766, USA.

Funding

Research Education Program to Promote Diversity in Immunologic and Allergic DiseasesR25AI179582 · NIAID · WESTERN UNIVERSITY OF HEALTH SCIENCES · PI Devendra K. Agrawal · 2025 to 2026
$756k
NIAID NIH HHS R25 AI179582
6 · The paper itself

Abstract

Chronic musculoskeletal conditions such as osteoarthritis and fibromyalgia make up a major portion of the disability population worldwide. An interplay among biological, psychological, and social factors influences the symptoms of these disorders. Treating these disorders requires a multidisciplinary approach, as a unimodal approach fails to produce long-term functional improvement. This review studies the role of biopsychosocial care in chronic pain management with an emphasis on the indications and limitations of the McKenzie Method of Mechanical Diagnosis and Therapy (MDT). MDT was compared with the effectiveness of physical therapy, occupational therapy, medication management, and psychological interventions, and its effectiveness was also examined when integrated into a multidisciplinary rehabilitation model. MDT has a limited role in centrally mediated conditions such as fibromyalgia, but it is superior in situations controlled by mechanism. MDT increases self-management, lowers disability, and reduces one's dependence on passive therapies. MDT is best seen as a mechanism-specific, patient-centered intervention integrated into a biopsychosocial framework. Ideal long-term outcomes in chronic musculoskeletal pain involve the integration of progressive exercise, occupational therapy, psychological intervention, targeted mechanical therapy, and medication management.

Indexed as

Biopsychosocial modelCentral sensitizationChronic musculoskeletal painFibromyalgiaMcKenzie MethodMechanical Diagnosis and Therapy (MDT)Multidisciplinary RehabilitationOsteoarthritis

Identifiers

PMID41948098
PMCPMC13052471

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.