Evidence map›Paper›PMID 41947973›Full record

ArticleCase reports in radiology2026

Congenital Toxoplasmosis With Atypical Neuroimaging: Hydrocephalus and Bilateral Chorioretinitis Without Intracranial Calcifications.

Saubhagya Dhakal, Pradeep Raj Regmi, Prajwal Dhakal, Binaya Adhikari, Shashi Shekhar Shingh, Basanta Sharma Paudel

Abstract read
In one paragraph

Article in Case reports in radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Saubhagya DhakalDepartment of Radiology and Imaging, Bir Hospital, National Academy of Medical Sciences, Kathmandu, Nepal, nams.org.np.ORCID https://orcid.org/0009-0004-5873-1911
Pradeep Raj RegmiDepartment of Radiology and Imaging, Tribhuvan University Teaching Hospital, Kathmandu, Nepal, teachinghospital.org.np.ORCID https://orcid.org/0000-0001-9571-9736
Prajwal DhakalDepartment of Radiology and Imaging, Tribhuvan University Teaching Hospital, Kathmandu, Nepal, teachinghospital.org.np.ORCID https://orcid.org/0000-0003-0500-2323
Binaya AdhikariDepartment of Radiology and Imaging, Tribhuvan University Teaching Hospital, Kathmandu, Nepal, teachinghospital.org.np.ORCID https://orcid.org/0000-0003-4281-0784
Shashi Shekhar ShinghDepartment of Radiology and Imaging, Tribhuvan University Teaching Hospital, Kathmandu, Nepal, teachinghospital.org.np.ORCID https://orcid.org/0009-0005-8921-1262
Basanta Sharma PaudelDepartment of Radiology and Imaging, Tribhuvan University Teaching Hospital, Kathmandu, Nepal, teachinghospital.org.np.ORCID https://orcid.org/0000-0002-7490-7989

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a rare case of congenital toxoplasmosis in a 2-month-old female infant from rural Nepal, born to a primigravida mother without prenatal care. The infant presented with progressive lethargy, feeding difficulties, intermittent fever, and progressive macrocephaly. Neuroimaging revealed obstructive hydrocephalus and multiple cerebral ring-enhancing lesions without intracranial calcifications. Ophthalmologic examination demonstrated bilateral chorioretinitis. Serologic testing confirmed congenital toxoplasmosis. Despite initiation of standard therapy with pyrimethamine, sulfadiazine, and folinic acid, the infant experienced clinical deterioration prior to planned neurosurgical intervention. This case highlights the clinical and radiologic variability of congenital toxoplasmosis, the diagnostic challenges in resource-limited settings, and the importance of recognizing atypical imaging patterns to guide timely management.

Indexed as

chorioretinitiscongenital toxoplasmosishydrocephalusneuroimagingprenatal careresource-limited setting

Identifiers

PMID41947973
PMCPMC13051784

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.