ArticleJournal of veterinary science2026
Behavioral and cardiorespiratory effects of a medetomidine and tramadol combination in horses.
Article in Journal of veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
importanceThe use of combinations of sedative and analgesic drugs during standing procedures in horses is necessary to provide reliable sedation with minimal ataxia and reduced responses to surgical or other stimuli in horses.
objectiveThis study assessed the behavioral and cardiorespiratory effects of medetomidine (M) administered with and without tramadol (T) in horses.
methodsEight horses were sedated intravenously with M (5 µg/kg) alone or with T (2 mg/kg) in a arandomized, blind, two-way crossover trial. Behavioral responses, including head height above the ground (HHAG), postural instability (PI), and response to pressure stimulus (RPS), and cardiorespiratory responses, including vital variables and blood analyses, were assessed following administration.
resultsThere were no clinically meaningful differences in cardiorespiratory values, HHAG, or PI between the groups. The RPS score over the scapula was significantly higher in the medetomidine and tramadol (MT) group ( CONCLUSIONS AND RELEVANCE: These results suggest that the MT combination may provide sufficient sedation and analgesia with minimal cardiorespiratory changes in horses.
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