Evidence map›Paper›PMID 41947649›Full record

ArticleJournal of cutaneous pathology2026

Adequacy of Single Random Skin Biopsy With Subcutaneous Sampling for the Diagnosis of Intravascular Lymphoma.

Phitsinee Purngpiputtrakul, Panitta Sitthinamsuwan, Sanya Sukpanichnant, Penvadee Pattanaprichakul, Manasmon Chairatchaneeboon, Yingyong Chinthammitr, Pochamana Phisalprapa

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Article in Journal of cutaneous pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Phitsinee PurngpiputtrakulDepartment of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Panitta SitthinamsuwanDepartment of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0002-8218-5787
Sanya SukpanichnantDepartment of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Penvadee PattanaprichakulDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Manasmon ChairatchaneeboonDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Yingyong ChinthammitrDivision of Hematology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Pochamana PhisalprapaDivision of Ambulatory Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRandom skin biopsy (RSB) is a valuable method for diagnosis of intravascular lymphoma (IVL). Previous studies have performed RSB at multiple locations. This study aimed to evaluate the adequacy of a single RSB site and the appropriate depth of the biopsies for diagnosing IVL.

methodsThe study included 209 patients who underwent RSB for IVL diagnosis. Sixty-six hematoxylin and eosin slides from 33 patients with a definitive diagnosis of IVL from RSB were analyzed for RSB site, blood vessel types, specimen depth, and tissue area containing detectable lymphoma cells.

resultsLymphoma cells were primarily detected in the capillaries of subcutaneous tissue (89.4%). The mean depth, tissue area of the specimens, and depth of the subcutaneous tissue were 12.7 mm, 151.2 mm

conclusionsA single RSB location, either at the abdomen or thigh, is adequate for diagnosing IVL in most patients under appropriate conditions. Biopsied specimens should have adequate subcutaneous fat to increase the likelihood of detecting lymphoma cells.

Indexed as

LymphomaSkinSkin NeoplasmsVascular NeoplasmsAdultAgedAged, 80 and overBiopsyFemaleHumansMaleMiddle AgedSubcutaneous Tissuecostintravascular lymphomalocationrandom skin biopsysiteworking time

Identifiers

PMID41947649
PMCPMC13341269

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.