Evidence map›Paper›PMID 41947562›Full record

Trial reportEuropean stroke journal2026

One-year functional outcome of the Flying Intervention Team versus patient interhospital transfer in acute ischaemic stroke.

Nikolai D Hubert, Markus Holler, Saskia R Wernsdorf, Sophie Herdegen, Christian Maegerlein, Hanni Wiestler, Lucie Esterl-Pfäffl, Dennis Dietrich, Thomas Witton-Davies, Isabel Heinrich and 5 more

Abstract readMulticenter StudyRandomized Controlled TrialComparative Study
In one paragraph

Trial report in European stroke journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Nikolai D HubertTEMPiS Telestroke Center, Department of Neurology, München Klinik, Academic Teaching Hospital of the Ludwig-Maximilians-University, Sanatoriumsplatz 2, Munich 81545, Germany.ORCID 0000-0001-9341-5018
Markus HollerTEMPiS Telestroke Center, Department of Neurology, München Klinik, Academic Teaching Hospital of the Ludwig-Maximilians-University, Sanatoriumsplatz 2, Munich 81545, Germany.ORCID 0000-0002-9196-2373
Saskia R WernsdorfTEMPiS Telestroke Center, Department of Neurology, München Klinik, Academic Teaching Hospital of the Ludwig-Maximilians-University, Sanatoriumsplatz 2, Munich 81545, Germany.
Sophie HerdegenTEMPiS Telestroke Center, Department of Neurology, München Klinik, Academic Teaching Hospital of the Ludwig-Maximilians-University, Sanatoriumsplatz 2, Munich 81545, Germany.
Christian MaegerleinTUM School of Medicine and Health, Klinikum Rechts der Isar, Technical University of Munich (TUM), Ismaninger Str. 22, Munich 81675, Germany.ORCID 0000-0003-4885-7671
Hanni WiestlerTEMPiS Telestroke Center, Department of Neurology, München Klinik, Academic Teaching Hospital of the Ludwig-Maximilians-University, Sanatoriumsplatz 2, Munich 81545, Germany.
Lucie Esterl-PfäfflTEMPiS Telestroke Center, Department of Neurology, München Klinik, Academic Teaching Hospital of the Ludwig-Maximilians-University, Sanatoriumsplatz 2, Munich 81545, Germany.
Dennis DietrichTEMPiS Telestroke Center, Department of Neurology, München Klinik, Academic Teaching Hospital of the Ludwig-Maximilians-University, Sanatoriumsplatz 2, Munich 81545, Germany.
Thomas Witton-DaviesDepartment of Diagnostic and Interventional Radiology, München Klinik, Sanatoriumsplatz 2, Munich 81545, Germany.
Isabel HeinrichTEMPiS Telestroke Center, Department of Neurology, München Klinik, Academic Teaching Hospital of the Ludwig-Maximilians-University, Sanatoriumsplatz 2, Munich 81545, Germany.
Anastasios MpotsarisDepartment of Diagnostic and Interventional Radiology, München Klinik, Sanatoriumsplatz 2, Munich 81545, Germany.ORCID 0000-0002-1275-8164
Philip M BathStroke Trials Unit, Mental Health & Clinical Neuroscience, University of Nottingham, Nottingham NG7 2UH, United Kingdom.ORCID 0000-0003-2734-5132
Heinrich J AudebertDepartment of Neurology, Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Campus Benjamin Franklin, Hindenburgdamm 30, Berlin 12200, Germany.ORCID 0000-0002-4785-0366
Roman L HaberlTEMPiS Telestroke Center, Department of Neurology, München Klinik, Academic Teaching Hospital of the Ludwig-Maximilians-University, Sanatoriumsplatz 2, Munich 81545, Germany.ORCID 0000-0003-0156-824X
Gordian J HubertTEMPiS Telestroke Center, Department of Neurology, München Klinik, Academic Teaching Hospital of the Ludwig-Maximilians-University, Sanatoriumsplatz 2, Munich 81545, Germany.ORCID 0000-0002-9463-0606

Funding

Bavarian Ministry of Health and NursingBjörn Steiger Foundation
6 · The paper itself

Abstract

introductionEndovascular thrombectomy is highly effective for large vessel occlusion strokes, yet timely access remains challenging in remote areas. The Flying Intervention Team study demonstrated that dispatching a neurointerventionist team to peripheral hospitals reduces time to treatment. This study evaluates 12-month functional outcomes of enrolled patients. PATIENTS AND

methodsThis is a secondary analysis of a multicentre pseudo-randomised controlled intervention study comparing 2 systems of care in alternating weeks. The study was conducted in 13 nonurban primary stroke centres in Bavaria, Germany. Of 157 patients enrolled between February 2018 and October 2019, 146 had available 12-month follow-up information. Patients were treated either by the flying team or after interhospital transfer to a referral centre. Primary outcome was the modified Rankin Scale (mRS) score at 12 months in the intention-to-treat analysis. Secondary outcomes included quality of life, activities of daily living and mortality.

resultsOverall, 146 patients were included (median [IQR] age, 75 [66-80] years; 79 [54%] women), 70 in the flying team group and 76 in the transfer group. Median decision-to-puncture time was 89 min shorter in the flying team group. No significant differences were found in successful reperfusion and complication rates. mRS scores at 12 months favoured the flying team (3 [IQR 1-6] vs 4 [2-6]; adjusted common odds ratio, 2.03; 95% CI, 1.09-3.84). Surviving patients had significantly better quality of life (EQ-5D mean [SD] utility score, 0.79 [0.24] vs 0.68 [0.31]). No significant differences were observed in Barthel index or mortality. DISCUSSION AND

conclusionIn rural stroke patients, deployment of a flying team was associated with better functional outcomes at 12 months. These findings reinforce the potential for broader implementation of the model to increase equitable access to stroke care.

Indexed as

Endovascular ProceduresIschemic StrokePatient Care TeamPatient TransferThrombectomyActivities of Daily LivingAgedAged, 80 and overFemaleGermanyHumansMaleQuality of LifeTime-to-TreatmentTreatment Outcomeacute ischaemic strokemechanical thrombectomymobile intervention teamstroke systems of caretelestroketime is brain

Identifiers

PMID41947562
PMCPMC13058261

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.