Evidence map›Paper›PMID 41947279›Full record

ArticleThe Laryngoscope2026

Transoral Robotic Resection of Pediatric Tongue Base Mucoepidermoid Carcinoma.

Krisztina Somogyvári, Kinga Jakab-Péter, Tamás Tornóczki, Krisztián Molnár, István Szanyi

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Article in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Krisztina SomogyváriDepartment of Otorhinolaryngology-Head and Neck Surgery, University of Pécs Medical School, Pécs, Hungary.ORCID https://orcid.org/0000-0002-6028-8048
Kinga Jakab-PéterDepartment of Otorhinolaryngology-Head and Neck Surgery, University of Pécs Medical School, Pécs, Hungary.
Tamás TornóczkiDepartment of Pathology, University of Pécs Medical School, Pécs, Hungary.
Krisztián MolnárDepartment of Medical Imaging, University of Pécs Medical School, Pécs, Hungary.
István SzanyiDepartment of Otorhinolaryngology-Head and Neck Surgery, University of Pécs Medical School, Pécs, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMucoepidermoid carcinoma (MEC) of the base of the tongue is exceedingly rare in the pediatric population. While transoral robotic surgery (TORS) has expanded minimally invasive options for oropharyngeal malignancies in adults, its application in pediatric tongue base tumors remains limited. This report aims to highlight the feasibility and oncologic adequacy of TORS in a carefully selected pediatric patient.

methodsWe report the case of a 13-year-old girl with low-grade MEC of the base of the tongue treated with TORS using the da Vinci Xi surgical system (Intuitive Surgical Inc.). Surgical duration, intraoperative findings, histopathologic features, and postoperative course were analyzed. Relevant literature regarding pediatric applications of TORS and alternative surgical approaches was reviewed.

resultsComplete en bloc resection with negative margins (R0) was achieved in 37 min without measurable blood loss. A branch of the right lingual artery was safely clipped under robotic visualization. The postoperative course was uneventful, and nasogastric feeding was maintained until postoperative Day 7. Histopathologic analysis confirmed low-grade MEC with negative margins and demonstrated MAML2 rearrangement in more than 50% of tumor cells by fluorescence in situ hybridization. No adjuvant therapy was indicated.

conclusionTransoral robotic surgery may represent a safe, minimally invasive, and oncologically appropriate surgical option for carefully selected pediatric patients with tongue base mucoepidermoid carcinoma. Further multicenter studies are warranted to better define long-term oncologic and functional outcomes in this population. LEVEL OF EVIDENCE: N/A.

Indexed as

Carcinoma, MucoepidermoidNatural Orifice Endoscopic SurgeryRobotic Surgical ProceduresTongue NeoplasmsAdolescentFemaleHumansmucoepidermoid carcinomapediatric head and neck oncologysalivary gland neoplasmstongue basetransoral robotic surgery

Identifiers

PMID41947279
PMCPMC13460464

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.