Evidence map›Paper›PMID 41947254›Full record

ArticleMicrobiome2026

Ethical design as a prerequisite for translational microbiome science.

Jo-Ann S Passmore, Abigail Nieves Delgado, Anna-Ursula Happel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiome, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jo-Ann S PassmoreCentre for Epidemic Response and Innovation (CERI), Stellenbosch University, Tygerberg, South Africa.
Abigail Nieves DelgadoFreudenthal Institute, Utrecht University, Utrecht, The Netherlands.
Anna-Ursula HappelDepartment of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa. anna.happel@uct.ac.za.

Funding

Bifidobacterium infantis supplementation in early life to improve neurodevelopment in infants exposed to HIVK43TW012864 · FIC · UNIVERSITY OF CAPE TOWN · PI Anna-Ursula Happel · 2024 to 2026
$305k
Bill & Melinda Gates Foundation INV-037612FIC NIH HHS K43 TW012864Gates Foundation INV-037612Nederlandse Organisatie voor Wetenschappelijk Onderzoek VI.Vidi.221F.014NIH HHS K43TW012864
6 · The paper itself

Abstract

Human microbiome research is expanding globally, yet remains dominated by samples, institutions, and leadership from the Global North. This imbalance undermines scientific validity, as microbiomes are shaped by socio-ecological context and temporal dynamics, and risks producing diagnostics and therapeutics that are not applicable across diverse populations. In this comment, we engage with van Daele et al.'s framework of co-laboration and argue for ethical, interdisciplinary, and locally led research models that center community participation, context-rich metadata, and equitable authorship. We outline structural requirements-governance tools, funding mechanisms, and accountability systems-needed to ensure these frameworks are implemented and advance both scientific integrity and global health equity. Video Abstract.

Indexed as

MicrobiotaTranslational Research, BiomedicalTranslational Science, BiomedicalGlobal HealthHumansCo-laborationEquitable partnershipsGlobal health equityHuman microbiomeRegulatory scienceTranslational ethics

Identifiers

PMID41947254
PMCPMC13054970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.