Evidence map›Paper›PMID 41947051›Full record

ArticleBMC geriatrics2026

Exploring how older adults perceived the impact of infectious diseases and vaccines on ageing: a cross-sectional study in France.

Alexandra Addario, Gaëtan Gavazzi, Thomas Célarier, Boris Chapoton, Nathalie Barth, Bienvenu Bongue, Elisabeth Botelho-Nevers

Abstract read
In one paragraph

Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexandra AddarioGérontopôle Auvergne-Rhône-Alpes, Saint-Etienne, France. alexandra.addario@chu-st-etienne.fr.ORCID 0000-0001-7461-6834
Gaëtan GavazziGroupe de Translational Research In Autoimmunity and Inflammation Group (T-RAIG, TIMC IMAG), Université de Grenoble-Alpes, Grenoble, France.ORCID 0000-0001-8375-7153
Thomas CélarierGérontopôle Auvergne-Rhône-Alpes, Saint-Etienne, France.
Boris ChapotonCoactis UR 4161, Université Jean Monnet Saint-Etienne, Saint-Etienne, France.
Nathalie BarthGérontopôle Auvergne-Rhône-Alpes, Saint-Etienne, France.
Bienvenu BongueChaire Sante des ainés, Ingénierie de la Prévention, PRESAGE Institute, Université Jean Monnet, Saint-Etienne, 42023, France.
Elisabeth Botelho-NeversCentre International de Recherche en Infectiologie, Team GIMAP, Université Jean Monnet, Université Claude Bernard Lyon 1, Inserm, U1111, CNRS, UMR530, Saint-Etienne, France.ORCID 0000-0003-2773-7750

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis cross-sectional study examined perceptions of health and ageing, and their influence on vaccine acceptance among individuals aged 65 and older living at home in the Auvergne-Rhône-Alpes region of France.

methodsAnonymous online questionnaires were distributed to users of CARSAT Rhône-Alpes (N1 = 50,000) and Auvergne (N2 = 9,597). The 62-question survey covered vaccination perceptions, the impact of the Covid-19 pandemic, health concerns, preventive measures, health information sources, and vaccination history. Vaccine hesitancy was assessed using the 5 C model, categorizing respondents into the group ‘Opposed’, ‘Hesitant’, and ‘Very Favourable’ to vaccination based on vaccination history and reasons for non-vaccination.

resultsOut of 3,331 respondents, 2,416 questionnaires were analysable. Most participants identified stroke (43.4%), cancer (20.4%), and dementia (18%) as primary health concerns. Infectious diseases ranked lowest, with pneumonia (1.24%), Covid-19 (0.89%), influenza (0.43%), and shingles (0.11%) infrequently cited. The Hesitant group more frequently questioned vaccination recommendations (82%) compared to the Very Favourable group (74%). Opposed participants significantly doubted vaccine efficacy and its role in healthy aging, differing from Hesitant and Very Favourable participants (p < 0.001). Perceptions of vulnerability to infection and beliefs about the seriousness of vaccine-preventable diseases significantly differed among groups (p < 0.001), with higher agreement in the Very Favourable group. Health-preservation behaviours, like regular medical check-ups and vaccination, were more common among the Very Favourable group, with no correlation found between diet, physical activity, and vaccination status.

conclusionsThe worry of infectious diseases is low compared to fear of disability. Differences in perceptions of infection vulnerability and vaccine efficacy highlight the need for targeted communication to enhance vaccine acceptance.

Indexed as

AgingCommunicable DiseasesCOVID-19VaccinationVaccination HesitancyAgedAged, 80 and overCross-Sectional StudiesFemaleFranceHumansMaleSurveys and QuestionnairesDisabilityHealthy agingOlder adultsVaccine hesitancy

Identifiers

PMID41947051
PMCPMC13191976

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.