ArticleMedical image analysis2026
PRIME: Phase reversed interleaved multi-Echo acquisition enables highly accelerated distortion-corrected diffusion MRI.
Article in Medical image analysis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Combined ADC and TMagnetic resonance in medicine · 2026Article
- Microstructure.jl: A Julia package for probabilistic microstructure model fitting with diffusion MRI.Imaging neuroscience (Cambridge, Mass.)Article
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16 authors.
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Abstract
High-resolution diffusion MRI (dMRI) is often constrained by the fundamental trade-off between geometric distortion, signal-to-noise ratio (SNR), and scan efficiency. The purpose of this study is to develop and evaluate a new pulse sequence for highly accelerated distortion-corrected dMRI by inserting additional echoes without prolonging TR, when generalized slice dithered enhanced resolution (gSlider) radiofrequency encoding is used for volumetric acquisition. A phase-reversed interleaved multi-echo acquisition (PRIME) was developed for rapid, high-resolution, and distortion-corrected dMRI, which includes multiple echoes where the first echo is for target diffusion-weighted imaging (DWI) acquisition with high-resolution and additional echoes are acquired with either lower resolution for 1) high-fidelity field map estimation, 2) phase navigation for shot-to-shot phase correction, 3) motion navigation across diffusion directions, or with high resolution to enable 4) high-fidelity diffusion relaxometry acquisitions. The sequence was evaluated on in vivo data acquired from healthy volunteers on clinical and Connectome 2.0 scanners. In vivo experiments demonstrated that 1) high in-plane acceleration was achieved using the high-fidelity field maps estimated from the second echo, which was made at a lower resolution/acceleration to increase its SNR while matching the effective echo spacing of the first readout, 2) high-resolution diffusion relaxometry parameters were estimated from triple-echo PRIME data using a white matter model of multi-TE spherical mean technique (MTE-SMT), and 3) high-fidelity mesoscale DWI at 490 µm isotropic resolution was obtained in vivo by capitalizing on the high-performance gradients of the Connectome 2.0 scanner. The proposed PRIME sequence enabled highly accelerated, high-resolution, and distortion-corrected dMRI using additional echoes without prolonging scan time when gSlider encoding is utilized.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.