Evidence map›Paper›PMID 41945533›Full record

ArticleJACC. Case reports2025

Distal Left Main Coronary Artery Aneurysm in the Absence of Coronary Artery Disease.

Mariel T Sullivan, Nicolas M Karam, Constantinos J Lovoulos

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mariel T SullivanDepartment of Medicine, The University of Vermont Medical Center, Burlington, Vermont, USA. Electronic address: mariel.sullivan@uvmhealth.org.
Nicolas M KaramDivision of Cardiovascular Medicine, Department of Medicine, The University of Vermont Medical Center, Burlington, Vermont, USA.
Constantinos J LovoulosDivision of Cardiothoracic Surgery, Department of Surgery, The University of Vermont Medical Center, Burlington, Vermont, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft main coronary artery (LMCA) aneurysms are exceedingly rare and most commonly associated with coronary artery disease. CASE SUMMARY: We report the case of a 70-year-old man with frequent runs of nonsustained ventricular tachycardia who was found to have a distal LMCA aneurysm without significant coronary artery disease. He was managed medically because of complex anatomy and minimal symptom burden. DISCUSSION: LMCA aneurysms are typically discovered incidentally during ischemic evaluation in association with hemodynamically significant coronary artery disease with reports often noting concomitant critical stenoses. Management in this case was complicated by involvement of the left main trifurcation. This patient's autoimmune neuromuscular disease and glucocorticoid exposure may have contributed to aneurysm formation. TAKE-HOME MESSAGES: Symptom burden is an important consideration in management decisions even in cases of giant LMCA aneurysms particularly if they are located distally. Blood pressure and heart rate regulation as well as serial imaging may be appropriate in certain cases.

Indexed as

autoimmunecoronary angiographycoronary vessel anomalyelectrophysiologyleft-sided catheterizationventricular tachycardia

Identifiers

PMID41945533
PMCPMC12802589

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.