ArticleProceedings of the National Academy of Sciences of the United States of America2026
Whole-genome combinatorial gene fusions generate novel genes for advanced microbial trait development.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Whole-genome combinatorial gene fusions generate novel genes for advanced microbial trait development.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
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Authors and funding
6 authors.
Funding
Abstract
Translational fusion of two separate genes into a compound sequence encoding a fusion protein is a key evolutionary mechanism which underpins the emergence of new protein activities, families, and architectures. In biotechnology, gene fusion is a valuable molecular evolution tool for tagging proteins of interest and for combining or altering protein activities. To broadly demonstrate and harness the gain-of-function capabilities of fusion genes in a whole-genome approach, we constructed a "Function Generator™" fusion gene library containing pairwise combinations of 5,019 protein-coding sequences in the
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Registered trials
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