Evidence map›Paper›PMID 41945439›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Transient ion-mediated interactions regulate subunit rotation in a eukaryotic ribosome.

George Wanes, Udayan Mohanty, Paul C Whitford

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Transient ion-mediated interactions regulate subunit rotation in a eukaryotic ribosome.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

George WanesCenter for Theoretical Biological Physics, Northeastern University, Boston, MA 02115.ORCID 0009-0007-8605-7938
Udayan MohantyDepartment of Chemistry, Boston College, Chestnut Hill, MA 02467.
Paul C WhitfordCenter for Theoretical Biological Physics, Northeastern University, Boston, MA 02115.ORCID 0000-0001-7104-2265

Funding

Elucidating the mechanisms that enable translation in bacterial and eukaryotic ribosomesR35GM153502 · NIGMS · NORTHEASTERN UNIVERSITY · PI Paul Charles Whitford · 2024 to 2026
$1.3M
HHS | National Institutes of Health (NIH) R35GM153502-02National Science Foundation (NSF) MCB-1915843National Science Foundation (NSF) PHY-2019745NIGMS NIH HHS R35 GM153502
6 · The paper itself

Abstract

While it is well known that ion binding can stabilize RNA structure, little is known about how transient/probabilistic ionic interactions facilitate biologically relevant conformational rearrangements. To address this, we developed a theoretical model that employs all-atom resolution with a simplified representation of biomolecular energetics (i.e., a structure-based "SMOG" model), explicit electrostatics, and ions (K

Indexed as

RibosomesIonsKineticsMagnesiumModels, MolecularNucleic Acid ConformationRotationSaccharomyces cerevisiaeStatic ElectricityThermodynamicsIonsMagnesiumconformational transitionelongationionsRNAsimulation

Identifiers

PMID41945439
PMCPMC13080003

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.