Evidence map›Paper›PMID 41945382›Full record

ArticleeLife2026

Single-cell RNA-seq reveals trans-sialidase-like superfamily gene expression heterogeneity in

Lucas Inchausti, Lucia Bilbao, Vanina A Campo, Joaquín Garat, José Sotelo-Silveira, Gabriel Rinaldi, Virginia M Howick, Maria A Duhagon, Javier G De Gaudenzi, Pablo Smircich

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lucas InchaustiLaboratorio de Bioinformática, Departamento de Genómica, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay.ORCID https://orcid.org/0009-0009-7089-6213
Lucia BilbaoLaboratorio de Bioinformática, Departamento de Genómica, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay.ORCID https://orcid.org/0009-0009-8895-1516
Vanina A CampoInstituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0003-2096-5988
Joaquín GaratDepartamento de Genómica, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay.ORCID https://orcid.org/0009-0005-5505-8036
José Sotelo-SilveiraDepartamento de Genómica, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay.ORCID https://orcid.org/0000-0002-4758-8556
Gabriel RinaldiDepartment of Biology, University of Oxford, Oxford, United Kingdom.ORCID https://orcid.org/0000-0002-7767-4922
Virginia M HowickSchool of Biodiversity, One Health and Veterinary Medicine, University of Glasgow, Glasgow, United Kingdom.ORCID https://orcid.org/0000-0003-3054-2460
Maria A DuhagonSección Genómica Funcional, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay.ORCID https://orcid.org/0000-0001-6468-1704
Javier G De GaudenziInstituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín-Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0001-8349-8833
Pablo SmircichLaboratorio de Bioinformática, Departamento de Genómica, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay.ORCID https://orcid.org/0000-0002-3856-3920

Funding

CSIC, Universidad de la Republica I+D-2020-505UNSAM INVESTIGA 2025 80020250100103SM
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

GlycoproteinsNeuraminidaseProtozoan ProteinsTrypanosoma cruziAnimalsChagas DiseaseGenetic HeterogeneityMultigene FamilyRNA-SeqSingle-Cell AnalysisSingle-Cell Gene Expression AnalysisTranscriptomeGlycoproteinsNeuraminidaseProtozoan Proteinstrans-sialidasechromosomesgene expressionhost-pathogen interactionsinfectious diseasemicrobiologySingle-cell RNA-seqtranscriptional heterogeneitytrans-sialidase-like superfamilyTrypanosoma cruzi

Identifiers

PMID41945382
PMCPMC13056360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.