Evidence map›Paper›PMID 41945127›Full record

ArticleBioprocess and biosystems engineering2026

Heavy metal dynamics in microalgae-based lead mitigation and contamination assessment in liquid biofuel production.

Jerin James, Afreen Parveen, Manisha Nanda, Sanjay Kumar, Afzal Hussain, Jin Huang, Krishna Kumar Jaiswal, Vinod Kumar, Jyoti Rawat

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Article in Bioprocess and biosystems engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Jerin JamesAlgal Research and Bioenergy Laboratory, Department of Food Science and Technology, Graphic Era (Deemed to be University), Dehradun, 248002, India.
Afreen ParveenAlgal Research and Bioenergy Laboratory, Department of Food Science and Technology, Graphic Era (Deemed to be University), Dehradun, 248002, India.
Manisha NandaDepartment of Microbiology, Graphic Era (Deemed to be University), Dehradun, 248002, India.
Sanjay KumarAlgal Research and Bioenergy Laboratory, Department of Food Science and Technology, Graphic Era (Deemed to be University), Dehradun, 248002, India.
Afzal HussainDepartment of Pharmacognosy, College of Pharmacy King Saud University, Riyadh, Kingdom of Saudi Arabia.
Jin HuangCollege of Ecology and Environment, Chengdu University of Technology, Chengdu City, 610059, China.
Krishna Kumar JaiswalBioprocess Engineering Laboratory, Department of Green Energy Technology, Pondicherry University, Puducherry, 605014, India.
Vinod KumarAlgal Research and Bioenergy Laboratory, Department of Food Science and Technology, Graphic Era (Deemed to be University), Dehradun, 248002, India. vinodkdhatwalia@gmail.com.
Jyoti RawatDepartment of Biosciences, School of Liberal Arts and Sciences, Mody University of Science and Technology, Lakshmangarh, Sikar, Rajasthan, 223211, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microalgae are increasingly being explored for heavy metal (HM) mitigation and biofuel production due to their sustainability and potential for high lipid yields. However, environmental contaminants like lead pose significant challenges to both biomass cultivation and downstream biorefinery process. This study investigates the dynamics of lead exposure in Scenedesmus abundans, assessing its lead bioaccumulation capacity and subsequent effects on biofuel integrity. The lead toxicity threshhold in S. abundans was assessed by determining the half-maximal inhibitory concentration (IC50) for Pb (II), which was found to be 280 ppm and its simultaneous impact on pigment composition and macromolecular content. The bioaccumulation of Pb (II) in the microalgae biomass reached 146.6 ppm. Pb (II) contamination was also recorded in the biomass extracted lipid fractions and the transesterified biodiesel. Hydrothermal Liquefaction (HTL) products like bio-oil and bio-char exhibited variations in lead contamination across different HTL temperatures. FTIR of the biomass and the bio-oil indicate that lead exposure disrupts the normal cellular composition in S. abundans triggering biochemical changes that help mitigate stress induced damage. SEM and EDX analyses indicate homogeneous presence of lead on biochar surface.

Indexed as

BiofuelsLeadMetals, HeavyMicroalgaeScenedesmusBiomassBiofuelsLeadMetals, HeavyBio-dieselBio-oilHeavy metal bioaccumulationHeavy metal dynamicsLead contaminationMicroalgae remediationSustainable energy

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.