ArticleRice (New York, N.Y.)2026
The miR396f-GRF7 Module Confers Thermotolerance in Rice.
Article in Rice (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Investigating the Role of MicroRNA396 (miR396) Gene in Regulating Wheat Yield and Grain Nitrogen Concentration.Plants (Basel, Switzerland) · 2026Article
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Authors and funding
9 authors.
Funding
Abstract
Heat stress is one of the major threats to global rice production globally. Uncovering key genetic regulators of thermotolerance is crucial for breeding climate-resilient crops. While microRNA396 (miR396) is known to be heat-responsive, the function and mechanism of its specific member, miR396f, remain elusive. Here, we report that miR396f is a heat-induced miRNA exhibiting predominantly in vascular bundles. Its transcriptional induction was more pronounced in a thermotolerant variety (HT54) than in a heat-sensitive one (HT14), correlating with natural variation in its promoter sequence. Through a multi-step screening, we identified growth-regulation factor 7 (GRF7) as its direct target under heat stress. Genetic evidence demonstrated that the miR396f-GRF7 module positively regulates thermotolerance at both the seedling and flowering stages: miR396f knockout lines (396fKO) were heat-sensitive, whereas GRF7 knockout lines (grf7) exhibited enhanced thermotolerance. Transcriptome analysis of grf7 mutant under heat stress suggested its potential involvement in sugar metabolism pathways. Our study unveils the miR396f-GRF7 module as a novel positive regulator of rice thermotolerance, providing valuable genetic targets for future breeding programs.
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