Evidence map›Paper›PMID 41944951›Full record

ArticleBulletin of experimental biology and medicine2026

Erythrocyte Integrity, Thymocyte Volume Regulation, and Functional State of the Heart during Ischemia/Reperfusion in Rats with Type 2 Diabetes Mellitus.

O J Khamidova, N D Oljaev, D D Fayziev, P G Merzlyak, R Sh Kurbannazarova, M Z Maksudov, R Z Sabirov, I F Abdullaev

Abstract read
PubMed Publisher
In one paragraph

Article in Bulletin of experimental biology and medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

O J KhamidovaInstitute of Biophysics and Biochemistry, National University of Uzbekistan, Tashkent, Republic of Uzbekistan.
N D OljaevInstitute of Biophysics and Biochemistry, National University of Uzbekistan, Tashkent, Republic of Uzbekistan.
D D FayzievInstitute of Biophysics and Biochemistry, National University of Uzbekistan, Tashkent, Republic of Uzbekistan.
P G MerzlyakInstitute of Biophysics and Biochemistry, National University of Uzbekistan, Tashkent, Republic of Uzbekistan.
R Sh KurbannazarovaInstitute of Biophysics and Biochemistry, National University of Uzbekistan, Tashkent, Republic of Uzbekistan.
M Z MaksudovInstitute of Biophysics and Biochemistry, National University of Uzbekistan, Tashkent, Republic of Uzbekistan.
R Z SabirovInstitute of Biophysics and Biochemistry, National University of Uzbekistan, Tashkent, Republic of Uzbekistan. zairovich@gmail.com.
I F AbdullaevInstitute of Biophysics and Biochemistry, National University of Uzbekistan, Tashkent, Republic of Uzbekistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the streptozotocin-nicotinamide model of type 2 diabetes mellitus (T2DM), erythrocytes exhibit increased resistance to osmotic and colloid-osmotic lysis. For thymocytes, cell volume regulation in T2DM was found to be significantly less effective than in the control. Using the Langendorff isolated heart retrograde perfusion model, we demonstrated that reperfusion after 30-min global ischemia leads to a dramatic decrease in HR, a decrease in left-ventricular systolic pressure, left-ventricular developed pressure, and the rate of left-ventricular pressure rise and fall. While the general pattern of heart dynamics during ischemia/reperfusion was preserved in T2DM, post-reperfusion HR was significantly lower than in the control.

Indexed as

Diabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2ErythrocytesMyocardial Reperfusion InjuryThymocytesAnimalsCell SizeMaleRatscell volume regulationerythrocytesischemia/reperfusion injurythymocytestype 2 diabetes mellitus

Identifiers

PMID41944951

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.