ReviewBulletin of experimental biology and medicine2026
Pharmacological Effects of Humic Substances and the Signaling Mechanisms of Their Implementation.
Review in Bulletin of experimental biology and medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
The analysis of current data and our own research findings have shown that humic substances represent a promising group of natural compounds with diverse pharmacological properties, including immunotropic, cardio-, neuro-, hepatoprotective, vasodilatory, antibacterial, and antiviral effects. The review presents information on therapeutic applications of humic substances derived from various sources and pharmaceutical preparations based on them in the treatment of diabetes, HIV infection, myocardial and cerebral ischemia, colitis, and some other pathological conditions. Research on the pro-apoptotic and anti-melanogenic effects of these compounds will enhance the effectiveness of existing approaches in the treatment of malignant tumors. This review presents data on the use of humic substances for developing novel drug delivery systems with tailored functionalities as a promising strategy in clinical oncology. Humic acids from peat exhibit stress-relief activity comparable to that of standard medications and preventive effects against exercise-induced fatigue. The review analyzes the intracellular mechanisms that play a key role in the realization of the effects of humic substances.
Indexed as
Identifiers
41944950What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.