Evidence map›Paper›PMID 41944936›Full record

ArticleBulletin of experimental biology and medicine2026

Efficacy of Single and Fractionated Neutron Irradiation of Normal and Tumor Cells In Vitro.

E V Koryakina, A A Pichkunova, M V Troshina, V I Potetnya, V O Saburov, E V Litun, A A Lychagin, S N Koryakin, S A Ivanov, A D Kaprin

Abstract read
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Article in Bulletin of experimental biology and medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

E V KoryakinaA. Tsyb Medical Radiological Research Center - Branch of National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninsk, Russia. ek-koryakina@mrrc.obninsk.ru.
A A PichkunovaA. Tsyb Medical Radiological Research Center - Branch of National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninsk, Russia.
M V TroshinaA. Tsyb Medical Radiological Research Center - Branch of National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninsk, Russia.
V I PotetnyaA. Tsyb Medical Radiological Research Center - Branch of National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninsk, Russia.
V O SaburovA. Tsyb Medical Radiological Research Center - Branch of National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninsk, Russia.
E V LitunA. Tsyb Medical Radiological Research Center - Branch of National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninsk, Russia.
A A LychaginA. Tsyb Medical Radiological Research Center - Branch of National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninsk, Russia.
S N KoryakinA. Tsyb Medical Radiological Research Center - Branch of National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninsk, Russia.
S A IvanovA. Tsyb Medical Radiological Research Center - Branch of National Medical Research Radiological Center, Ministry of Health of the Russian Federation, Obninsk, Russia.
A D KaprinPeoples' Friendship University of Russia Named after Patrice Lumumba (RUDN University), Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied the effect of 14.5 MeV neutron dose ultrafractionation on survival and recovery kinetics from radiation damage in normal V-79 and tumor B14-150 cells. Neutron doses of 0.5, 2, 4, and 6 Gy were split into 1, 2, 3, and 4 fractions. The observed recovery times 1.6 h (V-79) and 0.94 h (B14-150) indicate the possibility of reducing radiation damage with increasing the number of fractions. It was shown that neutron irradiation efficacy decreases when intervals between fractions exceed 1 h.

Indexed as

Fast NeutronsNeutronsCell Line, TumorCell SurvivalDose Fractionation, RadiationDose-Response Relationship, RadiationHumanscell survivalfast neutronsfractionated irradiationnormal cellstumor cells

Identifiers

PMID41944936

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.