Evidence map›Paper›PMID 41944928›Full record

ReviewCurrent treatment options in oncology2026

Advanced Mucosal Melanoma Therapies: Current Status and Future Directions.

Yiqun Zhang, Dawei Zhao, Di Wu

Abstract readReview
In one paragraph

Review in Current treatment options in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. [European journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Interleukin-8 in health and disease.Molecular biomedicine · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yiqun ZhangDepartment of Oncology, Cancer Center, The First Hospital of Jilin University, 1 Xinmin St, Changchun, 130021, China.
Dawei ZhaoDepartment of Breast Tumor, Jilin Cancer Hospital, No.1066 Jinhu Road, Changchun, 130012, China. DaweiZhao2020@163.com.ORCID http://orcid.org/0009-0002-1109-3110
Di WuDepartment of Oncology, Cancer Center, The First Hospital of Jilin University, 1 Xinmin St, Changchun, 130021, China. wudi1971@jlu.edu.cn.ORCID http://orcid.org/0000-0003-1870-798X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

opinion statementMucosal melanoma (MM) represents a rare malignancy in Caucasian populations but constitutes one of the predominant melanoma subtypes among non-Caucasian ethnic groups. Due to its anatomic occult nature, a significant proportion of patients with MM present with advanced-stage disease at diagnosis. Characterized by distinct genomic profiles and an immunosuppressive tumor microenvironment, MM exhibits suboptimal responses to current targeted drugs and immune checkpoint inhibitors (ICIs). Combination immunotherapy can overcome immune evasion by enhancing the infiltration of tumor-specific antigen-reactive T lymphocytes, thereby exhibiting potentiated anti-tumor activity. However, the rarity of MM has posed significant barriers to better understanding immunotherapy resistance mechanisms and investigating novel therapies. Consequently, there is a critical unmet need for establishing standardized treatment guidelines to improve survival outcomes in advanced MM. This article comprehensively reviews current status in the treatment of advanced MM. It also discusses potential future directions for treatment based on recent advances from clinical trials and basic research.

Indexed as

MelanomaMucous MembraneBiomarkers, TumorCombined Modality TherapyDisease ManagementHumansImmune Checkpoint InhibitorsImmunotherapyMolecular Targeted TherapyNeoplasm StagingPrognosisTreatment OutcomeTumor MicroenvironmentBiomarkers, TumorImmune Checkpoint InhibitorsCombination therapyImmunotherapyMucosal melanomaTargeted therapy

Identifiers

PMID41944928
PMCPMC13056740

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.