Evidence map›Paper›PMID 41944887›Full record

ArticleJournal of molecular medicine (Berlin, Germany)2026

Impact of acute blue light irradiation on the molecular clock and markers associated with photoaging in skin cell models.

Agnia Vibriani, Xinyue Chen, Susumu Kajiwara, Kanami Orihara

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular medicine (Berlin, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Agnia VibrianiSchool of Life Science and Technology, Institute of Science Tokyo, Yokohama, 226-8501, Japan.
Xinyue ChenSchool of Life Science and Technology, Institute of Science Tokyo, Yokohama, 226-8501, Japan.
Susumu KajiwaraSchool of Life Science and Technology, Institute of Science Tokyo, Yokohama, 226-8501, Japan.
Kanami OriharaSchool of Life Science and Technology, Institute of Science Tokyo, Yokohama, 226-8501, Japan. korihara@life.isct.ac.jp.ORCID http://orcid.org/0000-0002-2652-4529

Funding

Koyanagi Foundation 22050081Shiseido Group the 15th Shiseido Female Researcher Science GrantTojuro Iijima Foundation for Food Science and Technology 2024
6 · The paper itself

Abstract

The increased reliance on digital devices in our daily lives has exposed humans to intense levels of high-energy blue light. However, the harmful effects of blue light irradiation on human skin are less understood than UV irradiation. Notably, we demonstrated that blue light induces skin photoaging through a novel mechanism involving disruption of the circadian rhythm. An in vitro study using human keratinocyte cells and dermal fibroblasts was conducted. The results showed that blue light irradiation triggers cellular senescence and downregulates key aging-associated markers, including extracellular matrix components, epithelial barrier protein, NAD

Indexed as

SkinSkin AgingBiomarkersBlue LightCellular SenescenceCircadian RhythmFibroblastsHumansKeratinocytesBiomarkersBlue lightChronotherapyCircadian rhythmPeripheral clockSkin photoaging

Identifiers

PMID41944887
PMCPMC13056783

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.