Evidence map›Paper›PMID 41944847›Full record

ReviewArchives of microbiology2026

Advances, opportunities, and challenges in microbial community construction: from environmental remediation to biomanufacturing.

Mengxue Li, Xiang Xing, Kangqing Fei, Zhenni Cheng, Jiayu Zhang, Rongbo Guo, Xiaokui Zhang, Shanfei Fu, Xiaolei Fan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mengxue LiShandong Industrial Engineering Laboratory of Biogas Production & Utilization, Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, NO. 189 Songling Road, Laoshan District, Qingdao, 266101, Shandong, People's Republic of China.
Xiang XingMarine College, Shandong University, No. 180, Wenhua West Road, Huancui District, Weihai, 264209, Shandong, China. Xingxiang@sdu.edu.cn.
Kangqing FeiShandong Industrial Engineering Laboratory of Biogas Production & Utilization, Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, NO. 189 Songling Road, Laoshan District, Qingdao, 266101, Shandong, People's Republic of China.
Zhenni ChengShandong Industrial Engineering Laboratory of Biogas Production & Utilization, Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, NO. 189 Songling Road, Laoshan District, Qingdao, 266101, Shandong, People's Republic of China.
Jiayu ZhangShandong Industrial Engineering Laboratory of Biogas Production & Utilization, Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, NO. 189 Songling Road, Laoshan District, Qingdao, 266101, Shandong, People's Republic of China.
Rongbo GuoShandong Industrial Engineering Laboratory of Biogas Production & Utilization, Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, NO. 189 Songling Road, Laoshan District, Qingdao, 266101, Shandong, People's Republic of China.
Xiaokui ZhangMarine College, Shandong University, No. 180, Wenhua West Road, Huancui District, Weihai, 264209, Shandong, China.
Shanfei FuShandong Industrial Engineering Laboratory of Biogas Production & Utilization, Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, NO. 189 Songling Road, Laoshan District, Qingdao, 266101, Shandong, People's Republic of China.
Xiaolei FanShandong Industrial Engineering Laboratory of Biogas Production & Utilization, Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, NO. 189 Songling Road, Laoshan District, Qingdao, 266101, Shandong, People's Republic of China. fanxl@qibebt.ac.cn.

Funding

he Key Technology Research, Development and Industrialization Demonstration Project of Qingdao No. 25-1-1-gjgg-78-nshShandong Postdoctoral Science Foundation SDBX202302016the China Postdoctoral Science Foundation NO. 2024M753352the Qingdao New Energy Shandong Laboratory Open Project QNESL OP202311the Taishan Scholars Program NO. tsqn202312268
6 · The paper itself

Abstract

The construction of artificial microbial communities entails the rational design and assembly of multiple microorganisms into tailored consortia, enabling the execution of specific biological functions under controlled conditions. Propelled by advances in synthetic biology, systems biology, and multi-omics technologies, this strategy has emerged as a promising solution to overcome the inherent limitations of monocultures and natural microbial communities—such as narrow metabolic versatility, poor environmental adaptability, and low controllability—thus exhibiting considerable potential in environmental remediation and biomanufacturing for the sustainable production of high-value compounds. To optimize consortium performance, cross-disciplinary approaches have been developed, including integrating the Design-Build-Test-Learn (DBTL) framework with advanced analytical tools to decipher microbial spatiotemporal interactions, and using AI-driven dynamic modeling to integrate multi-omics data. Future efforts combining dynamic modeling, AI optimization, and cross-disciplinary collaboration will be key to addressing existing challenges. Supplementary measures, such as developing automated equipment and establishing standardized safety frameworks, will further enhance scalability and commercial potential. Ultimately, these advances will fully unlock the capacity of artificial taxa to drive green and sustainable innovations in environmental and industrial fields.

Indexed as

Environmental Restoration and RemediationMicrobial ConsortiaBiodegradation, EnvironmentalMultiomicsSynthetic BiologySystems BiologyBiomanufacturingEnvironmental remediationMicrobial community constructionSynthetic biology

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.