Evidence map›Paper›PMID 41944727›Full record

ArticleMicrobial genomics2026

Functional shifts of the dual-substrate phosphoribosyl isomerase PriA from primary to specialized metabolism in rare Actinomycetota.

Luis Rodrigo Rosas-Becerra, Andrés Arredondo-Cruz, Nelly Sélem-Mojica, Francisco Barona-Gómez

Abstract read
In one paragraph

Article in Microbial genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luis Rodrigo Rosas-BecerraEvolution of Metabolic Diversity Laboratory. Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (Cinvestav-IPN), Irapuato, Guanajuato, México.
Andrés Arredondo-CruzCentro de Ciencias Matemáticas, UNAM, Morelia, Michoacán, Mexico.
Nelly Sélem-MojicaCentro de Ciencias Matemáticas, UNAM, Morelia, Michoacán, Mexico.
Francisco Barona-GómezInstitute of Biology Leiden, Leiden University, Leiden, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evolutionary functional innovations can occur while gene families expand and two homologous (or analogous) genes co-occur. PriA is a dual-substrate enzyme family exclusive to

Indexed as

ActinobacteriaBacterial ProteinsEvolution, MolecularGenome, BacterialMultigene FamilyPhylogenySubstrate SpecificityBacterial ProteinsActinomycetotaadechlorinbiosynthetic gene clusterenzyme evolutiongene expansiongenome miningPriA

Identifiers

PMID41944727
PMCPMC13055916

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.