Evidence map›Paper›PMID 41944628›Full record

ArticleMacromolecular bioscience2026

Sulfonated Hyaluronic Acid-Based Polymers and Hydrogels Using Thiol-Ene and Thiol-Michael Reactions.

Ivo Anton Octave Beeren, Pieter Jelle Dijkstra, Ane Albillos Sanchez, Jopeth Ramis, Francesca Perin, Carlos Mota, Sandra Camarero-Espinosa, Lorenzo Moroni, Matthew Brandon Baker

Abstract read
In one paragraph

Article in Macromolecular bioscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ivo Anton Octave BeerenDepartment of Complex Tissue Regeneration, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0003-4829-9956
Pieter Jelle DijkstraDepartment of Complex Tissue Regeneration, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, Maastricht, The Netherlands.
Ane Albillos SanchezDepartment of Complex Tissue Regeneration, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, Maastricht, The Netherlands.
Jopeth RamisDepartment of Complex Tissue Regeneration, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, Maastricht, The Netherlands.
Francesca PerinDepartment of Complex Tissue Regeneration, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, Maastricht, The Netherlands.
Carlos MotaDepartment of Complex Tissue Regeneration, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0001-5935-6245
Sandra Camarero-EspinosaDepartment of Complex Tissue Regeneration, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, Maastricht, The Netherlands.
Lorenzo MoroniDepartment of Complex Tissue Regeneration, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0003-1298-6025
Matthew Brandon BakerDepartment of Complex Tissue Regeneration, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0003-1731-3858

Funding

European Research CouncilHorizon2020 #637308ON/EORS #21-362
6 · The paper itself

Abstract

Non-sulfated polysaccharides like hyaluronic acid (HA) have been widely studied as scaffold material for tissue engineering applications. To mimic the function of sulfated glycosaminoglycan in the matrix, sulfate groups can be grafted. However, here, harsh reaction conditions are required which induce significant backbone degradation. As an alternative, sulfonates (R-SO

Indexed as

Hyaluronic AcidHydrogelsPolymersSulfhydryl CompoundsSulfonic AcidsMaleimidesMorpholinesNorbornanesTissue Engineering4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chlorideHyaluronic AcidHydrogelsmaleimideMaleimidesMorpholinesNorbornanesPolymersSulfhydryl CompoundsSulfonic Acidscarboxylic acid activationhyaluronic acidsulfonated hydrogelssulfonation

Identifiers

PMID41944628
PMCPMC13055429

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.