Evidence map›Paper›PMID 41944190›Full record

ArticleLab on a chip2026

A 3D microfluidic model of exchange between perfused blood and lymphatic microvascular networks.

Delaney Gray-Scherr, Terry Ching, Katherine Beran, Sarah C Adams, Emily Davis, Abraham C I van Steen, Trisha Raman, Wilson W Wong, Jeroen Eyckmans, Christopher S Chen

Abstract read
In one paragraph

Article in Lab on a chip, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Delaney Gray-ScherrDepartment of Biomedical Engineering and the Biological Design Center, Boston University, Boston, MA 02215, USA. chencs@bu.edu.ORCID 0000-0003-3515-5152
Terry ChingDepartment of Biomedical Engineering and the Biological Design Center, Boston University, Boston, MA 02215, USA. chencs@bu.edu.ORCID 0000-0002-5747-2020
Katherine BeranDepartment of Biomedical Engineering and the Biological Design Center, Boston University, Boston, MA 02215, USA. chencs@bu.edu.ORCID 0009-0002-0696-2975
Sarah C AdamsDepartment of Biomedical Engineering and the Biological Design Center, Boston University, Boston, MA 02215, USA. chencs@bu.edu.ORCID 0000-0002-9527-8157
Emily DavisDepartment of Biomedical Engineering and the Biological Design Center, Boston University, Boston, MA 02215, USA. chencs@bu.edu.ORCID 0009-0000-2740-1451
Abraham C I van SteenDepartment of Biomedical Engineering and the Biological Design Center, Boston University, Boston, MA 02215, USA. chencs@bu.edu.ORCID 0000-0002-8023-352X
Trisha RamanDepartment of Biomedical Engineering and the Biological Design Center, Boston University, Boston, MA 02215, USA. chencs@bu.edu.ORCID 0009-0009-4329-9472
Wilson W WongDepartment of Biomedical Engineering and the Biological Design Center, Boston University, Boston, MA 02215, USA. chencs@bu.edu.ORCID 0000-0001-8394-889X
Jeroen EyckmansDepartment of Biomedical Engineering and the Biological Design Center, Boston University, Boston, MA 02215, USA. chencs@bu.edu.ORCID 0000-0003-1475-8149
Christopher S ChenDepartment of Biomedical Engineering and the Biological Design Center, Boston University, Boston, MA 02215, USA. chencs@bu.edu.ORCID 0000-0003-2445-8449

Funding

Project-005UL1TR001430 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BAIR-MERRITT, MEGAN H, CENTER, DAVID M. · 2015 to 2024
$52.3M
Synthetic vascularization and regeneration in engineered tissuesR01EB033821 · NIBIB · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI SANGEETA N. BHATIA, CHRISTOPHER S CHEN · 2023 to 2026
$2.2M
Structure, function, and mechanobiology of a compression-sensitive cell-cell junctionR01HL175072 · NHLBI · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI CHRISTOPHER S CHEN · 2025 to 2026
$1.3M
NCATS NIH HHS UL1 TR001430NHLBI NIH HHS R01 HL175072NIBIB NIH HHS R01 EB033821Wellcome Leap HOPE ProgramWellcome Trust
6 · The paper itself

Abstract

Blood and lymphatic microvascular networks function as integrated systems within tissues, exchanging fluid, molecules, and cells to regulate homeostasis and immune responses, yet current

Indexed as

Lymphatic VesselsMicrofluidic Analytical TechniquesMicrovesselsAnimalsCell MovementEndothelial CellsHumansMicrophysiological SystemsPerfusionT-Lymphocytes

Identifiers

PMID41944190
PMCPMC13054795

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.