Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
28 authors.
Giovanni PerettoMultidisciplinary Disease Unit for Myocarditis and Arrhythmogenic Cardiomyopathies IRCCS San Raffaele Scientific Institute Milan Italy.ORCID 0000-0003-1815-4000
Nicolas PiriouNantes Université, CHU Nantes, CNRS, INSERM, Institut du Thorax, Centre de Réferénce Cardiomyopathies Nantes France.ORCID 0000-0002-6677-6552
Alessio GasperettiDivision of Cardiology, Department of Medicine Johns Hopkins University School of Medicine Baltimore MD USA.ORCID 0000-0003-3432-070X
Barbara BauceDepartment of Cardiac, Thoracic and Vascular Sciences, Cardiology Unit Padua University Hospital Padua Italy.ORCID 0000-0001-7357-293X
Andrea VillatoreMultidisciplinary Disease Unit for Myocarditis and Arrhythmogenic Cardiomyopathies IRCCS San Raffaele Scientific Institute Milan Italy.ORCID 0000-0002-2858-1404
Alessia F TrezzaMultidisciplinary Disease Unit for Myocarditis and Arrhythmogenic Cardiomyopathies IRCCS San Raffaele Scientific Institute Milan Italy.ORCID 0009-0003-2337-2851
Alex MelotNantes Université, CHU Nantes, CNRS, INSERM, Institut du Thorax, Centre de Réferénce Cardiomyopathies Nantes France.
Anna PalmisanoMultidisciplinary Disease Unit for Myocarditis and Arrhythmogenic Cardiomyopathies IRCCS San Raffaele Scientific Institute Milan Italy.ORCID 0000-0002-1564-2060
Giulia BassettoDivision of Cardiology, Cardiothoracovascular Department Azienda Sanitaria Universitaria Giuliano Isontina and University of Trieste Trieste Italy.ORCID 0009-0003-9269-5806
Marika MartiniDepartment of Cardiac, Thoracic and Vascular Sciences, Cardiology Unit Padua University Hospital Padua Italy.ORCID 0009-0000-0522-8408
Cinzia RadesichDivision of Cardiology, Cardiothoracovascular Department Azienda Sanitaria Universitaria Giuliano Isontina and University of Trieste Trieste Italy.ORCID 0000-0003-2345-2758
Alessia PaldinoDivision of Cardiology, Cardiothoracovascular Department Azienda Sanitaria Universitaria Giuliano Isontina and University of Trieste Trieste Italy.ORCID 0000-0002-5823-3777
Maria PerottoDivision of Cardiology, Cardiothoracovascular Department Azienda Sanitaria Universitaria Giuliano Isontina and University of Trieste Trieste Italy.ORCID 0000-0001-8252-2934
Eric D SmithDepartment of Internal Medicine, Division of Cardiovascular Medicine University of Michigan Ann Arbor MI USA.ORCID 0000-0002-5915-9492
Monica De GaspariDepartment of Cardiac, Thoracic and Vascular Sciences, Cardiovascular Pathology Unit Padua University Hospital Padua Italy.ORCID 0000-0001-9528-4883
Stefania RizzoDepartment of Cardiac, Thoracic and Vascular Sciences, Cardiovascular Pathology Unit Padua University Hospital Padua Italy.ORCID 0000-0002-8575-1748
Kalliopi PilichouDepartment of Cardiac, Thoracic and Vascular Sciences Genetic Unit, Padua University Hospital Padua Italy.ORCID 0000-0003-3646-0669
Antonio EspositoMultidisciplinary Disease Unit for Myocarditis and Arrhythmogenic Cardiomyopathies IRCCS San Raffaele Scientific Institute Milan Italy.ORCID 0000-0002-1170-6266
Maurizio PieroniDepartment of Experimental and Clinical Medicine University of Florence, Careggi University Hospital Florence Italy.ORCID 0000-0002-6830-4292
Gianfranco SinagraDivision of Cardiology, Cardiothoracovascular Department Azienda Sanitaria Universitaria Giuliano Isontina and University of Trieste Trieste Italy.ORCID 0000-0003-2700-8478
Cristina BassoDepartment of Cardiac, Thoracic and Vascular Sciences, Cardiovascular Pathology Unit Padua University Hospital Padua Italy.ORCID 0000-0002-0195-9753
Adam HelmsDepartment of Internal Medicine, Division of Cardiovascular Medicine University of Michigan Ann Arbor MI USA.ORCID 0000-0002-0234-6430
Paolo Della BellaCardiac Electrophysiology Department IRCCS San Raffaele Scientific Institute Milan Italy.ORCID 0000-0001-8346-1387
Marco MerloDivision of Cardiology, Cardiothoracovascular Department Azienda Sanitaria Universitaria Giuliano Isontina and University of Trieste Trieste Italy.ORCID 0000-0002-1022-3131
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
backgroundDesmosomal "hot-phase" cardiomyopathy (HPC), characterized by bursts of myocardial inflammation mimicking acute myocarditis (AM), carries relevant risks of adverse outcomes. This study aimed to identify diagnostic "red flags" favoring HPC over AM.
methodsPatients (n=134) receiving a first diagnosis of AM, proven by endomyocardial biopsy or cardiac magnetic resonance plus troponin elevation, were retrospectively identified at a referral center. HPC was defined by presence of pathogenic desmosomal gene variants (DGVs). Clinical, imaging, and electrical features were compared between HPC cases and controls with gene-negative AM to identify red flags. Diagnostic algorithms were derived and tested in an external multicenter cohort of DGV carriers (n=30).
resultsPatients with HPC (n=22; 91%
conclusionsMyocarditis in DGV carriers predominantly affects young women. A red flag-based approach improves recognition of desmosomal HPC over classic AM.
Indexed as
CardiomyopathiesDesmosomesMyocarditisAcute DiseaseAdultAlgorithmsBiopsyDesmoplakinsDiagnosis, DifferentialFemaleGenetic Predisposition to DiseaseHumansMaleMiddle AgedMyocardiumPredictive Value of TestsDesmoplakinsTroponinarrhythmiascardiomyopathydesmoplakindesmosomalhot‐phasemyocarditis
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.