Evidence map›Paper›PMID 41944126›Full record

ArticleActa crystallographica. Section F, Structural biology communications2026

Crystal structures of Escherichia coli glucokinase acetylation-mimicking variants and insights into the impact of acetylation.

Joseph Andrews, Joshua Sakon, Chenguang Fan

Abstract read
In one paragraph

Article in Acta crystallographica. Section F, Structural biology communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joseph AndrewsDepartment of Chemistry and Biochemistry, University of Arkansas, Fayetteville, Fayetteville, AR 72701, USA.
Joshua SakonDepartment of Chemistry and Biochemistry, University of Arkansas, Fayetteville, Fayetteville, AR 72701, USA.ORCID 0000-0002-8373-969X
Chenguang FanDepartment of Chemistry and Biochemistry, University of Arkansas, Fayetteville, Fayetteville, AR 72701, USA.

Funding

Understanding Hesitant AdoptersP20GM103429 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI Lawrence E Cornett, JERRY WARE · 2012 to 2026
$60.9M
Studying lysine aminoacylation of human metabolic enzymesR15GM159279 · NIGMS · UNIVERSITY OF ARKANSAS AT FAYETTEVILLE · PI FAN, CHENGUANG · 2025 to 2025
$563k
NIGMS NIH HHS R15 GM159279NIH HHS P20GM103429NIH HHS R15GM159279
6 · The paper itself

Abstract

In this study, we report the crystal structures of K214Q and K216Q variants of Escherichia coli glucokinase (ecGLK), each of which is bound to phosphate in the active-site cleft. The structure of the K214Q variant was determined at 2.70 Å resolution and refined with an R

Indexed as

acetylation-mimicking mutationsglucokinaseslysine acetylation

Identifiers

PMID41944126
PMCPMC13133996

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.