Evidence map›Paper›PMID 41943834›Full record

ArticleInternational journal of biological sciences2026

Apigenin Suppresses Bladder Cancer via the SIRT6-NCOA2-PPARα Axis.

Ying Liu, Zhen-Duo Shi, Yun-Fei Wei, Si-Yuan Jiang, Harsh Patel, Qian-Zi Liu, Yang Dong, Yi-Fang Liu, Lin Hao, Shan Gao and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of biological sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ying LiuSchool of Life Sciences, Jiangsu Normal University, Xuzhou, China.
Zhen-Duo ShiSchool of Life Sciences, Jiangsu Normal University, Xuzhou, China.
Yun-Fei WeiDepartment of Urology, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
Si-Yuan JiangZhongda Hospital, Medical School, Advanced Institute for Life and Health, Southeast University, Nanjing, China.
Harsh PatelDepartment of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York, USA.
Qian-Zi LiuJiangsu Provincial Engineering Research Center of Cancer Cell Therapy and Translational Medicine, Xuzhou Central Hospital, Southeast University, Xuzhou, China.
Yang DongDepartment of Urology, Xuzhou Central Hospital, Southeast University, Xuzhou, China.
Yi-Fang LiuJiangsu Provincial Engineering Research Center of Cancer Cell Therapy and Translational Medicine, Xuzhou Central Hospital, Southeast University, Xuzhou, China.
Lin HaoDepartment of Urology, Xuzhou Central Hospital, Southeast University, Xuzhou, China.
Shan GaoZhongda Hospital, School of Life Sciences and Technology, Advanced Institute for Life and Health, Southeast University, Nanjing, China.
Dong-Hua YangNew York College of Traditional Chines Medicine, Mineola, New York, USA.
Qiang LiXuzhou Institute of Agricultural Sciences in Jiangsu Xuhuai District, Key Laboratory of Biology and Genetic Breeding of Sweetpotato, Ministry of Agriculture and Rural Affairs, Sweetpotato Research Center, Xuzhou, China.
Cong-Hui HanSchool of Life Sciences, Jiangsu Normal University, Xuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein acetylation is increasingly recognized as a key regulator of tumor progression, yet natural compounds capable of modulating this modification remain poorly defined. Apigenin, a dietary flavonoid suppresses bladder cancer progression based on

Indexed as

ApigeninNuclear Receptor Coactivator 2PPAR alphaSirtuinsUrinary Bladder NeoplasmsAnimalsCell Line, TumorHumansMiceSignal TransductionApigeninNCOA2 protein, humanNuclear Receptor Coactivator 2PPAR alphaSirtuinsapigeninbladder cancermetabolic reprogrammingNCOA2SIRT6

Identifiers

PMID41943834
PMCPMC13050455

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.