Evidence map›Paper›PMID 41943821›Full record

ArticleJBMR plus2026

Follistatin-like protein 1 (FSTL1) modulates bone remodeling and attenuates bone loss in a mouse model of postmenopausal osteoporosis.

Hao Yuan, Bao-Rui Chen, Fu-Xing Han, Kai Huang, Zhi-Hao Jia, Ying-Ying Dong, Lin Bo

Abstract read
In one paragraph

Article in JBMR plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hao YuanDepartment of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.ORCID https://orcid.org/0009-0000-1032-6483
Bao-Rui ChenDepartment of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
Fu-Xing HanCAM-SU Genomic Resource Center, Soochow University, Suzhou, China.
Kai HuangCAM-SU Genomic Resource Center, Soochow University, Suzhou, China.
Zhi-Hao JiaCambridge-Suda Genomic Resource Center, Suzhou Medical College, Soochow University, Suzhou 215000, China.
Ying-Ying DongCAM-SU Genomic Resource Center, Soochow University, Suzhou, China.
Lin BoDepartment of Rheumatology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study systematically delineates the expression dynamics of follistatin-like protein 1 (FSTL1) in postmenopausal osteoporosis (PMOP) and elucidates its role in skeletal homeostasis. Integrated analyses of clinical serum samples and the GTEx database revealed a pronounced reduction in circulating FSTL1 levels in PMOP patients. In vivo, Fstl1

Indexed as

FSTL1Menopauseosteoblastsosteoclastspostmenopausal osteoporosis

Identifiers

PMID41943821
PMCPMC13050501

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.