Evidence map›Paper›PMID 41943804›Full record

ArticleOrthopaedic journal of sports medicine2026

Biomechanical Comparison of All-Suture Anchors Versus Interference Screws for Femoral Fixation in Pediatric MPFL Reconstruction.

Amin M Alayleh, Austin Stoner, Ian Hollyer, Kelly McFarlane, Nneoma Duru, Wills Baird, Calvin Chan, Nicole Pham, Henry B Ellis, Matthew R Schmitz and 4 more

Abstract read
In one paragraph

Article in Orthopaedic journal of sports medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

14 authors.

Amin M AlaylehDepartment of Orthopaedic Surgery, Stanford University School of Medicine, San Francisco, California, USA.ORCID https://orcid.org/0009-0001-1675-163X
Austin StonerDepartment of Orthopaedic Surgery, Stanford University School of Medicine, San Francisco, California, USA.ORCID https://orcid.org/0000-0002-3788-9347
Ian HollyerDepartment of Orthopaedic Surgery, Stanford University School of Medicine, San Francisco, California, USA.
Kelly McFarlaneDepartment of Orthopaedic Surgery, Stanford University School of Medicine, San Francisco, California, USA.
Nneoma DuruDepartment of Orthopaedic Surgery, Stanford University School of Medicine, San Francisco, California, USA.
Wills BairdDepartment of Orthopaedic Surgery, Stanford University School of Medicine, San Francisco, California, USA.
Calvin ChanDepartment of Orthopaedic Surgery, Stanford University School of Medicine, San Francisco, California, USA.
Nicole PhamDepartment of Orthopaedic Surgery, Stanford University School of Medicine, San Francisco, California, USA.
Henry B EllisDepartment of Orthopaedic Surgery, Scottish Rite for Children, Frisco, Texas, USA.ORCID https://orcid.org/0000-0001-5444-094X
Matthew R SchmitzDepartment of Orthopaedic Surgery, Rady Children's Hospital San Diego, San Diego, California, USA.
Marc TompkinsDepartment of Orthopaedic Surgery, University of Minnesota, Minneapolis, Minnesota, USA.ORCID https://orcid.org/0000-0002-8641-3150
Yi-Meng YenDepartment of Orthopaedic Surgery & Sports Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-1306-4201
Theodore GanleyDivision of Orthopaedic Surgery, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-6145-7835
Kevin G SheaDepartment of Orthopaedic Surgery, Stanford University School of Medicine, San Francisco, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pediatric patellofemoral instability is common, and medial patellofemoral ligament (MPFL) reconstruction is a highly effective treatment option. Femoral graft fixation methods include suture anchors (SAs) and interference screws (ISs), although comparative biomechanical studies in pediatric bone are lacking. Purpose: To compare the biomechanical properties of SA versus IS femoral graft fixation in pediatric MPFL reconstruction. Study Design: Controlled laboratory study. Methods: Ten fresh-frozen pediatric knees underwent femoral MPFL graft fixation using SA and IS (mean age, 9.5 years; range, 8-10 years). Posterior tibialis tendon allograft was used in both groups. For the IS group, 8-mm tunnels were drilled and 8 × 25-mm biocomposite IS was used for graft fixation. For the SA group, a 1.8-mm knotless all-suture SA was placed and secured to the graft. Specimens were loaded onto an Instron 5944 and subjected to cyclic preconditioning, followed by an ultimate failure load at 6 mm/s. The load displacement curve was then used to calculate stiffness (N/mm). Data were analyzed using repeated-measures analysis of variance to account for multiple measurements on the same specimens. Results: IS graft fixation demonstrated significantly higher ultimate failure load than SA (246.4 ± 79.7 N vs 90.4 ± 20.6 N, Conclusion: IS offers significantly higher ultimate failure load and stiffness values compared to SA femoral MPFL graft fixation in human pediatric knees. Mean ultimate failure load values for femoral MPFL fixation in pediatric bone may be lower than in adult bone, based on comparative adult studies. These results provide initial biomechanical data comparing 2 commonly used femoral fixation methods in skeletally immature patients. Clinical Relevance: This study characterized the biomechanical strength of SA and IS femoral MPFL fixation in pediatric bone, revealing differences in ultimate failure load and stiffness between constructs and compared to adult bone. While SA may pose less risk for growth alteration from physeal injury in younger patients, greater "time-zero" MPFL fixation strength with IS may allow for accelerated rehabilitation and earlier return to sport, which is a key patient and family satisfaction variable. In some circumstances, SA fixation may be preferred due to physeal proximity, and postoperative therapy regimens may be modified to account for lower fixation strength. These findings can help surgeons optimize implant selection, tailor rehabilitation protocols, and minimize the risk of graft failure in skeletally immature patients.

Indexed as

biomechanicscadaverinterference screwmedial patellofemoral ligamentMPFLpediatricsports medicinesuture anchor

Identifiers

PMID41943804
PMCPMC13050412

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.