ArticleClinical endoscopy2026
Linked color imaging versus artificial intelligence-assisted linked color imaging for neoplasia detection in the colorectum: a randomized trial in Brazil.
Article in Clinical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundAdenomas and sessile serrated lesions (SSLs) are neoplasms that play a role in colorectal cancer development. Improving adenoma detection rate (ADR) and SSL detection rates (SDR) allows for more effective prevention of colorectal cancer. Linked color imaging (LCI) and artificial intelligence (AI) have contributed to increased ADR and SDR. This study aimed to compare the neoplasia detection rates (NDR, adenomas, or SSLs) between LCI and AI-assisted LCI colonoscopy.
methodsWe conducted a prospective randomized trial to compare LCI with LCI+AI. We evaluated ADR, SDR, and NDR as the primary outcomes.
resultsA total of 779 polyps were detected in 622 patients (304 in the LCI group and 318 in the LCI+AI group); 555 were adenomas and 62 were SSLs for a total of 617 neoplastic lesions (79.2%) in 363 patients. Comparing the LCI and LCI+AI groups, the ADR, SDR, and NDR were 46.7% vs. 53.1% (p=0.13), 8.2% vs. 8.5% (p=0.90), and 52.3% vs. 56.6% (p=0.30), respectively. The mean number of adenomas per patient, advanced ADR, and withdrawal time did not significantly differ between the two groups.
conclusionsSimilar results were observed in both groups, and even with the good performance of AI-assisted LCI, LCI alone yielded high ADR, SDR, and NDR.
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