Evidence map›Paper›PMID 41943407›Full record

ArticleAnnals of African medicine2026

Prevalence of Oral Soft Tissue Lesions and Their Associations with Oral Hygiene Practices, Addictive Habits, and CD4 Counts Among Lesbian, Gay, Bisexual, Transgender, and Queer Individuals Living with Human Immunodeficiency Virus.

Shrikanth Muralidharan, Pramila Mallaiah, Deepak Bangera, Arunkumar Acharya, Judy Annie Koshy, Monali Nikalje

Abstract read
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Article in Annals of African medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Shrikanth MuralidharanDepartment of Research, National Institute of Naturopathy, Ministry of Ayush, Pune, Maharashtra, India.
Pramila MallaiahDepartment of Public Health Dentistry, MR Ambedkar Dental College and Hospital, Bengaluru, Karnataka, India.
Deepak BangeraResearch Officer (Yoga and Naturopathy), Central Council for Research in Yoga and Naturopathy, Ministry of Ayush, New Delhi, India.
Arunkumar AcharyaDepartment of Public Health Dentistry, The Oxford Dental College, Bengaluru, Karnataka, India.
Judy Annie KoshyDepartment of Periodontics, MA Rangoonwala College of Dental Sciences and Research Centre, Pune, Maharashtra, India.
Monali NikaljeDepartment of Dentistry, Symbiosis Medical College for Women, Symbiosis University Hospital and Research Centre, Symbiosis International (Deemed University), Pune, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOral manifestations often reflect underlying immune suppression and disease progression. These lesions can profoundly affect the quality of life, leading to pain, difficulty in eating, and social stigma. In the lesbian, gay, bisexual, transgender, and queer (LGBTQ) population living with human immunodeficiency virus (HIV), additional sociobehavioral factors, such as discrimination, mental health challenges, and barriers to healthcare access, may exacerbate oral health issues. MATERIAL AND

methodsThis cross-sectional study aimed to evaluate the prevalence of oral soft tissue lesions and their associations with oral hygiene practices, addictive habits, and CD4 counts in 56 LGBTQ adults with HIV (mean age 34.8 ± 7.2 years). Participants were recruited from an outpatient clinic and underwent comprehensive oral examinations using World Health Organization criteria, self-reported questionnaires on hygiene and addictions, and a review of recent CD4 counts.

resultsAll participants reported addictions, predominantly smoking (44.6%), smokeless tobacco (37.5%), and alcohol (30.3%), with polyaddiction in 39.3% of the participants. Soft-tissue lesions were detected in 60.7% of patients, including candidiasis (26.8%), oral hairy leukoplakia (14.3%), aphthous ulcers (10.7%), linear gingival erythema (8.9%), and tobacco pouch keratosis (7.1%). Lesion prevalence was significantly higher among irregular brushers (100%, P = 0.034), poly-addicts (86.4%, P = 0.002), and those with CD4 counts <350 cells/mm 3 (78.9% vs. 42.3% for ≥350 cells/mm 3 , P = 0.011). Specific associations included tobacco use and leukoplakia/keratosis ( P = 0.029) and alcohol use and candidiasis ( P = 0.041).

conclusionsMultidisciplinary interventions emphasizing oral hygiene education, addiction cessation programs, and integrated dental-HIV care are essential to reduce morbidity and enhance the overall well-being of LGBTQ individuals with HIV.

Indexed as

HIV InfectionsMouth DiseasesOral HygieneSexual and Gender MinoritiesAdultCD4 Lymphocyte CountCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceQuality of LifeSurveys and Questionnairesand queerbisexualgayGender DiverseHIVHuman immunodeficiency virusIndialesbianOraloral lesionstransgender

Identifiers

PMID41943407
PMCPMC13374991

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.