Evidence map›Paper›PMID 41943144›Full record

ArticleTrials2026

Human-centered design of an exercise intervention for adolescent cancer patients: findings from a patient involvement workshop to inform intervention development.

Dania Schütze, Jennifer Engler, Sarah Erhard, Micah Walker, Mirjam Dieckelmann

Abstract read
In one paragraph

Article in Trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Dania SchützeGoethe University Frankfurt, Institute of General Practice, Theodor-Stern-Kai 7, Frankfurt am Main, 60590, Germany. schuetze@allgemeinmedizin.uni-frankfurt.de.ORCID http://orcid.org/0000-0003-4788-2082
Jennifer EnglerGoethe University Frankfurt, Institute of General Practice, Theodor-Stern-Kai 7, Frankfurt am Main, 60590, Germany.ORCID http://orcid.org/0000-0002-6030-1513
Sarah ErhardGoethe University Frankfurt, Department of Pediatrics, University Hospital, Theodor-Stern-Kai 7, Frankfurt am Main, 60590, Germany.ORCID http://orcid.org/0009-0009-1419-8218
Micah WalkerGoethe University Frankfurt, Department of Pediatrics, University Hospital, Theodor-Stern-Kai 7, Frankfurt am Main, 60590, Germany.
Mirjam DieckelmannGoethe University Frankfurt, Department of Pediatrics, University Hospital, Theodor-Stern-Kai 7, Frankfurt am Main, 60590, Germany.ORCID http://orcid.org/0000-0002-5243-7840

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOnly few exercise trials have been conducted in the immediate time after a child's first cancer diagnosis. The Exercise CC Trial was designed to study the effects of exercise during the first 8 weeks following the diagnosis. However, young patients have not been involved in designing an exercise intervention in this care-intensive period of time in which complying with regular exercise regimens may be particularly difficult. To understand factors facilitating compliance and to prevent drop-outs in this critical period, this study aims to engage adolescents with cancer in designing an exercise intervention by incorporating patient perspectives in research development.

methodsA workshop was conducted with adolescents who had previously participated in exercise therapy during their cancer treatment. This interactive session allowed participants to share their experiences and contribute to the intervention design prior to enrolling patients in the trial. Data was collected through a group discussion, which was recorded and transcribed for qualitative content analysis using MAXQDA20 software, ensuring a comprehensive understanding of participants' views.

resultsThe workshop, attended by four patients aged 17 to 20, highlighted various aspects of exercise therapy. Participants valued the flexibility of choosing between various exercises and noted the psychological benefits of physical activity, which provided them with a constructive outlet and relief during treatment. They also appreciated the physical improvements and the motivational impact of monitoring progress. Importantly, the study revealed the need for personalized exercise regimes that consider individual physical conditions and preferences.

conclusionsWe present an innovative approach in pediatric exercise oncology inviting the perspectives of adolescents and young adults to participate in research and shape the design of intervention details during the care-intensive phase immediately following a cancer diagnosis. We describe our "lessons learned" in giving adolescents a voice and share their knowledge and insights into their specific needs and preferences of exercise regimens in trials. This approach ensures that intervention details align with young patients' expectations, which can be opposite to experts' assumptions.

trial registrationDRKS-ID: DRKS00032259. Registered on 10.07.2024.

Indexed as

Adolescent BehaviorExercise TherapyNeoplasmsPatient ParticipationResearch DesignAdolescentAge FactorsFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMotivationPatient ComplianceTime FactorsTreatment OutcomeYoung AdultAdolescentsExercise oncologyHuman-centered designPatient involvementPediatric oncology

Identifiers

PMID41943144
PMCPMC13067389

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.