Evidence map›Paper›PMID 41943143›Full record

ArticleAntimicrobial resistance and infection control2026

Appraising the infection prevention and control practices at two referral hospitals in Malawi: a mixed methods situational analysis.

Dorica Ng'ambi, Thomasena O'Byrne, Wala Kamchedzera, Donald Kanjere Zgambo, Raymond Pongolani, Rufaro Matorera, Hendrina Saini, Wilned Zoto Hara, Emmie Jingini, Alex Maseko and 7 more

Abstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Dorica Ng'ambiDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK. dorica.ngambi@lstmed.ac.uk.
Thomasena O'ByrneDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
Wala KamchedzeraDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
Donald Kanjere ZgamboMalawi Liverpool Wellcome Research Programme, Kamuzu University of Health Sciences, Blantyre, Malawi.
Raymond PongolaniMalawi Liverpool Wellcome Research Programme, Kamuzu University of Health Sciences, Blantyre, Malawi.
Rufaro MatoreraMalawi Liverpool Wellcome Research Programme, Kamuzu University of Health Sciences, Blantyre, Malawi.
Hendrina SainiZomba Central Hospital, Zomba, Malawi.
Wilned Zoto HaraQuality Management Unit, Queen Elizabeth Central Hospital, Blantyre, Malawi.
Emmie JinginiMalawi Liverpool Wellcome Research Programme, Kamuzu University of Health Sciences, Blantyre, Malawi.
Alex MasekoMalawi Liverpool Wellcome Research Programme, Kamuzu University of Health Sciences, Blantyre, Malawi.
Owen MusopoleQuality Management Directorate, Ministry of Health, Lilongwe, Malawi.
Saulos NyirendaZomba Central Hospital, Zomba, Malawi.
Kelvin MpondaDepartment of Dermatology, Queen Elizabeth Central Hospital, Blantyre, Malawi.
Gabriel Kambale BundukiDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
Maryse KokDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
Nicholas FeaseyDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
Tara TancredDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.

Funding

National Institute for Health and Care Research NIHR301627
6 · The paper itself

Abstract

introductionImplementation of infection prevention and control (IPC) practices can reduce healthcare associated infections (HAIs). There is limited insight into the implementation of IPC practices in the medical and surgical departments in Malawian hospitals. The study aimed to explore the current state of IPC policy/guidelines and their implementation gaps at two referral hospitals in Malawi.

methodsWe conducted a cross-sectional mixed-methods situational analysis to understand the IPC landscape in the medical and surgical departments in two tertiary hospitals from September 2023 to April 2024. These methods included: (i) document review; (ii) participant observation; (iii) semi-structured interviews with healthcare workers (HCWs); (iv) key informant interviews with hospital managers; and (v) focus group discussions with cleaning staff and patient-guardians. Quantitative data from participant observations were analysed in Excel to generate descriptive statistics, while framework analysis was used for qualitative data.

resultsIPC guidelines were theoretically available but inaccessible to most HCWs. Observation revealed low compliance to all five moments of hand hygiene (0-12%) and non-touch technique (9-25%), often due to a lack of IPC supplies and poor knowledge. Adherence to environmental cleaning between procedures in theatre was 50%. Training of HCWs on IPC was inconsistent, and monitoring and feedback mechanisms were largely absent. There was no clear monitoring schedule for aseptic procedures, hand hygiene, or environmental cleaning. There was limited orientation on IPC practices for patient-guardians.

conclusionWe observed critical IPC gaps in both hospitals. Addressing these issues requires thoughtful implementation of multiple context-specific IPC strategies that are likely to be sustainable, such as IPC orientation for patient-guardians as they play a critical role in the Malawian healthcare system. Training of HCWs, regular monitoring and feedback on HAI/IPC practices, easily accessible IPC guidelines and improved IPC infrastructure and supplies will facilitate improved IPC practices.

Indexed as

Cross InfectionInfection ControlCross-Sectional StudiesGuideline AdherenceHand HygieneHealth PersonnelHospitalsHumansMalawiTertiary Care CentersAseptic techniqueHand hygieneHealthcare associated infectionsHealthcare workersInfection prevention and controlMalawiPatient-guardians

Identifiers

PMID41943143
PMCPMC13188669

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.