ArticleAIDS research and therapy2026
Awareness, knowledge, perception and behavioral risk predictors of acceptability of long-acting injectable lenacapavir HIV pre-exposure prophylaxis in Ghana: a cross-sectional study.
Article in AIDS research and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Long-acting injectable HIV pre-exposure prophylaxis (PrEP), particularly lenacapavir, has demonstrated near-complete efficacy, yet its public health impact depends on community awareness, knowledge and acceptance. This cross-sectional study assessed awareness, knowledge, perceptions, acceptability, and predictors of lenacapavir use among adults in Ghana. We found awareness, knowledge, and perceptions were generally low, whilst acceptability was moderate (60.5%). Poor perception [(aOR = 0.12, 95% CI (0.05–0.29), p < 0.001)] and irregular exposure to online health information [(aOR = 0.24, 95% CI (0.07–0.77), p = 0.017)] were independently associated, 88.0% and 76.0% respectively, with lower acceptability. Targeted education, health worker engagement, and supportive policies are essential to facilitate lenacapavir uptake in Ghana.
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