Evidence map›Paper›PMID 41943020›Full record

ArticleBMC pediatrics2026

Screening Emotions in Adolescents Receiving Care at the Hospital for mild Traumatic Brain Injury (SEARCH-mTBI): protocol for a multicenter observational study.

Daniel K Nishijima, Nathan Kuppermann, Stacy J Suskauer, Kristy B Arbogast, Mohamed Badawy, T Charles Casper, Andrea T Cruz, Daniel J Corwin, Tiffani J Johnson, Elizabeth D Rosenthal and 6 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06370520 (Screening Emotions in Adolescents Receiving Care at the Hospital for mTBI), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06370520 recruitingnot on this map

Screening Emotions in Adolescents Receiving Care at the Hospital for mTBI (SEARCH-mTBI)

TypeobservationalSponsorUniversity of California, DavisRan2024 to 2028Enrolled2,592ConditionsBrain Injury Traumatic Mild, Brain Injuries, Brain Injuries, Acute, Head Injury With Intracranial HemorrhageArmsValidated Questionnaires, Questionnaires, Clinician / Medical Record Variables
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Differential Use of Central Outcomes Center to Maximize Follow-Up in a Study of Adolescents Seeking Care in the Emergency Department.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Daniel K NishijimaDepartment of Emergency Medicine, University of California Davis School of Medicine, 4150 V Street, PSSB Suite 2100, Sacramento, CA, 95817, USA. dnishijima@ucdavis.edu.
Nathan KuppermannDepartments of Pediatrics and Emergency Medicine, George Washington University School of Medicine and Health Science and Children's National Hospital, Washington, USA.
Stacy J SuskauerDepartments of Physical Medicine & Rehabilitation and Pediatrics, Kennedy Krieger Institute and Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Kristy B ArbogastDivision of Emergency Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Mohamed BadawyDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
T Charles CasperDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA.
Andrea T CruzDepartment of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Daniel J CorwinDivision of Emergency Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Tiffani J JohnsonDepartment of Emergency Medicine, University of California Davis School of Medicine, 4150 V Street, PSSB Suite 2100, Sacramento, CA, 95817, USA.
Elizabeth D RosenthalKennedy Krieger Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Stephanie M RuestDepartments of Emergency Medicine and Pediatrics, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Daniel J TancrediDepartment of Emergency Medicine, University of California Davis School of Medicine, 4150 V Street, PSSB Suite 2100, Sacramento, CA, 95817, USA.
Danny G ThomasDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
Mark R ZonfrilloDepartments of Emergency Medicine and Pediatrics, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Beth S SlomineKennedy Krieger Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
SEARCH-mTBI Study Group

Funding

Sleep and Circadian Dysfunction, Brain and Neurobehavioral Development in AutismP50HD103538 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI S. Ali Fatemi, Bradley L Schlaggar · 2020 to 2026
$9.9M
CDC HHS U01CE003573NICHD NIH HHS P50 HD103538
6 · The paper itself

Abstract

backgroundMild traumatic brain injury (mTBI) is a common pediatric condition with growing recognition of its impact on mental health. While most children recover within weeks of the injury, a subset experience persistent emotional symptoms, including anxiety and depression. Early identification of youth at risk for adverse mental health outcomes is essential for timely intervention. Our primary study objective is to develop a robust clinical prediction tool to identify children at risk for adverse mental health outcomes after mTBI.

methodsWe will conduct a multicenter prospective observational cohort study enrolling patients aged 11–17 years who present to the emergency department (ED) with mTBI within 3 days from injury. We will enroll consecutive patients into separate derivation and validation cohorts using different enrolling sites. Baseline data, including pre-injury mental health status, and clinical variables will be collected from patients, caregivers, and ED clinicians. We will collect validated measures during the acute period (1 to 2 weeks), 1-month, and 3-months post-injury including: the Generalized Anxiety Disorder-7 (GAD-7), Patient Health Questionnaire-8 (PHQ-8), Pediatric Quality of Life Inventory (PedsQL), Rivermead Post-Concussion Symptoms Questionnaire, and the Strengths and Difficulties Questionnaire (SDQ). Our primary outcome is a composite measure of clinically significant new or worsening in anxiety or depression at 1 or 3 months. Secondary outcomes include persistent post-concussive symptoms, reduced quality of life, and new behavioral or emotional difficulties. We will analyze associations between baseline factors and outcomes to derive and validate a clinical prediction tool. DISCUSSION: Our study will provide a comprehensive assessment of mental health and other outcomes following mTBI in adolescents and identify predisposing factors for adverse outcomes. Our findings will contribute to the development of a clinical prediction tool to support early identification and referral for at-risk youth. Study results may inform post-injury care pathways and targeted interventions aimed at improving long-term recovery.

trial registrationClinicalTrials.gov Identifier: NCT06370520. Registered March 20, 2024. The study protocol has been approved by the Institutional Review Boards at all participating sites.

Indexed as

AnxietyBrain ConcussionDepressionEmotionsAdolescentChildEmergency Service, HospitalFemaleHumansMaleMulticenter Studies as TopicObservational Studies as TopicProspective StudiesResearch DesignAdolescentsDisparitiesMental healthMild traumatic brain injuryObservational studyPrediction modelProtocol

Identifiers

PMID41943020
PMCPMC13191971

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.