ArticleBMC pediatrics2026
Predictive value of the lactate dehydrogenase to albumin ratio for coronary artery lesions and IVIG resistance in Kawasaki disease.
Article in BMC pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundEarly identifying coronary artery lesions (CALs), along with some children with Kawasaki disease (KD) don’t respond to intravenous immunoglobulin (IVIG), continues to be a crucial and hotly contested area of study in current medical research. This research sought to investigate the predictive significance of the lactate dehydrogenase to albumin ratio (LAR) in KD complicated with CALs and IVIG for the first time.
methodsA retrospective study was carried out on the medical files of patients diagnosed with Kawasaki disease who had been admitted to the pediatrics department at Shandong University Qilu Hospital from January 2016 through August 2023. Construct the nomogram model of KD complicated with CALs and IVIG resistance and performed internal validation. The nomogram's effectiveness was confirmed through the use of ROC curve and calibration curve.
resultsA total of 416 KD children were enrolled. LAR was significantly higher in patients with KD combined with CALs and IVIG resistance, serving as a predictive risk factor for both. The nomogram for CALs, constructed with gender, monocyte count (MON), mean platelet volume (MPV), albumin (ALB) and LAR as predictive risk factors, and the nomogram for IVIG resistance, incorporating white blood cell (WBC), MPV, ALB and LAR as predictive risk factors, both exhibited good discrimination (training/validation set area under the curves: 0.761/0.692 and 0.812/0.698) and calibration. LAR had moderate predictive value for both outcomes.
conclusionsElevated level of LAR was closely associated with the occurrence of CALs and IVIG resistance. This suggests that LAR could potentially serve as an emerging predictor for CALs progression and IVIG resistance in KD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.