ArticleBMC plant biology2026
PfWRI1-10 transcription factor mediates lipid synthesis in Perilla frutescens through regulating PfBCCP1 gene transcription.
Article in BMC plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Selection and Validation of Reference Genes for RT-qPCR Analysis of Lipid Biosynthesis-Related Genes inPlants (Basel, Switzerland) · 2026Article
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10 authors.
Funding
Abstract
backgroundPerilla frutescens is an oilseed crop rich in unsaturated fatty acids (UFAs). WRINKLED1 (WRI1) is an AP2/EREBP-type transcription factor (TF), which plays important regulation roles in fatty acid (FA) metabolism.
resultsIn this study, 11 PfWRI1 members were identified in the perilla genome. qRT-PCR analysis revealed that PfWRI1-10 was expressed higher than other members in developing seeds of perilla, suggesting that PfWRI1-10 may play crucial roles in seed oil biosynthesis. Overexpression of PfWRI1-10 resulted in enhancement of total oil content by 9.75% and α-linolenic acid (C18:3) level by 0.43%, while the soluble sugar content decreased in the transgenic tobacco leaves. qRT-PCR showed that the expression levels of glycolysis gene (NtPKp-β1) and FA biosynthesis genes (NtACP1 and NtBCCP1) significantly upregulated, whereas NtKAS1-B expression was downregulated in transgenic tobacco plants, indicating that PfWRI1-10 reallocated carbon sources flow to facilitate lipid biosynthesis by regulating the expression of the target genes. Yeast one-hybrid (Y1H) assays demonstrate that PfWRI1-10 directly binds to the AW-box cis-element of the PfBCCP1 promoter. Overexpression of PfBCCP1 enhanced the lipid content in the transgenic yeast, confirming its function in lipid metabolism.
conclusionsPfWRI1-10 transcription factor promotes lipid biosynthesis by upregulating PfBCCP1 and other lipid related genes. The current findings provide a scientific basis for the in-depth analysis of the regulatory network of perilla oil biosynthesis and also valuable genes for genetic improvement of perilla oil yield and quality.
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