ArticleScientific reports2026
Harnessing the potential of Alcaligenes faecalis for optimum biodegradation of norfloxacin spiked wastewater using response surface methodology.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The use of antibiotics is increasing and they enter water untreated. These antibiotics tendency to bioaccumulate and contribute to bacterial resistance. This study is designed to explore and optimize the potential of resistant bacteria for the treatment of norfloxacin (NOR) antibiotic spiked wastewater. The Alcaligenes faecalis ABR-14 was isolated from wastewater and sludge samples and was identified using 16S rRNA sequencing (Macrogen Inc. Geumchen-gu, South Korea). The 1515 bp was submitted in NCBI Genbank and the accession number of ‘PV364597.1’ was obtained. The results demonstrated that Alcaligenes faecalis ABR-14 efficiently broke down NOR reaching 96% degradation at 100 mg/L in 10 days under ideal circumstances such as 35 °C, pH 6.5, sodium acetate, NH4Cl and 105 CFU/mL. Two significate parameters (pH and Nitrogen (N) source), one less-significant parameter (inoculum density) and 3 non-significant parameters (antibiotic concentration, temperature and Carbon (C) source) based on Central Composite Design (CCD) and Response Surface Methodology (RSM) were revealed. The Hanes plot gives straight line, where R2 is 0.99, Vmax = 200.21, Km = 133.4. The plot between experimental and predicted values represent the best fit of the values based on straightness (R2 = 0.91). ANOVA for CCD present the p value below 0.05 which represents the significance and critically important factors. This study is among the first highlights the potential application of Alcaligenes faecalis ABR-14 for norfloxacin biodegradation. The generation of non-toxic metabolites makes this eco-friendly and sustainable. The abilities of such resistant microbes can be utilized in future to develop NOR contaminated wastewater treatment plant.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.