Evidence map›Paper›PMID 41942665›Full record

ArticleBulletin of experimental biology and medicine2026

Association of CLOCK rs1801260 Polymorphism with Sleep Quality in Residents of the Far North.

D G Gubin, S N Kolomeychuk, M F Borisenkov, I M Petrov, A A Markov, Yu A Petrova, K A Voronin, M S Mezhakova, Yu V Boldyreva, V A Markov and 1 more

Abstract read
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Article in Bulletin of experimental biology and medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

D G GubinTyumen State Medical University, Ministry of Health of the Russian Federation, Tyumen, Russia. dgubin@mai.ru.
S N KolomeychukTyumen State Medical University, Ministry of Health of the Russian Federation, Tyumen, Russia.
M F BorisenkovInstitute of Chemistry, Komi Science Center, Ural Branch of the Russian Academy of Sciences, Syktyvkar, Komi Republic, Russia.
I M PetrovTyumen State Medical University, Ministry of Health of the Russian Federation, Tyumen, Russia.
A A MarkovTyumen State Medical University, Ministry of Health of the Russian Federation, Tyumen, Russia.
Yu A PetrovaTyumen State Medical University, Ministry of Health of the Russian Federation, Tyumen, Russia.
K A VoroninTyumen State Medical University, Ministry of Health of the Russian Federation, Tyumen, Russia.
M S MezhakovaTyumen State Medical University, Ministry of Health of the Russian Federation, Tyumen, Russia.
Yu V BoldyrevaTyumen State Medical University, Ministry of Health of the Russian Federation, Tyumen, Russia.
V A MarkovTyumen State Medical University, Ministry of Health of the Russian Federation, Tyumen, Russia.
A U ShigabaevaTyumen State Medical University, Ministry of Health of the Russian Federation, Tyumen, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a longitudinal study of permanent Arctic residents, an actigraphic analysis of sleep quality indicators across different seasons revealed no significant overall seasonal differences in sleep efficiency (p = 0.487). However, TT homozygotes for the CLOCK gene rs1801260 polymorphism the exhibited lower sleep efficiency, particularly in spring and summer. Multiple linear regression, incorporating categorical covariates including rs1801260 polymorphism, sex, season, indigenous status, age, and body mass index, identified the TT genotype as the sole significant predictor of sleep efficiency (β = -0.215; p = 0.029), confirming its association with poorer sleep quality.

Indexed as

CLOCK ProteinsPolymorphism, Single NucleotideSleepSleep QualityActigraphyAdultArctic RegionsFemaleGenotypeHumansLongitudinal StudiesMaleSeasonsCLOCK protein, humanCLOCK ProteinsactigraphyArcticCLOCK genegenetic predictorssleep quality

Identifiers

PMID41942665

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.