Evidence map›Paper›PMID 41942414›Full record

ArticleThe Eurasian journal of medicine2026

From MASLD to MELD 3.0: Integrating the Spectrum of Liver Disease Risk Stratification into Primary Care.

Pavan Kumar Reddy Kalluru, Nirmal Onteddu, Lourdhu Pragna Reddy Onteddu, Shivani Thota, Apoorva Cherukuri, Hossein Rajali, Kalyan Naik Gugulothu

Abstract read
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Article in The Eurasian journal of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Pavan Kumar Reddy KalluruDepartment of Internal Medicine, West Anaheim Medical Center, Anaheim, California, USA.
Nirmal OntedduDepartment of Internal Medicine, University of Florida College of Medicine, Jacksonville, USA.
Lourdhu Pragna Reddy OntedduDepartment of Health Sciences, University of Ottawa, Ottawa, Canada.
Shivani ThotaDepartment of Gastroenterology, Kamineni Institute of Medical Sciences, Narkatpalli, India.
Apoorva CherukuriDepartment of Internal Medicine, West Anaheim Medical Center, Anaheim, California, USA.
Hossein RajaliDepartment of Internal Medicine, West Anaheim Medical Center, Anaheim, California, USA.
Kalyan Naik GugulothuDepartment of Physical Diagnosis, American University of Anguilla School of Medicine, Anguilla.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 2023, key advancements in liver disease were introduced into practice. Metabolic dysfunction-associated steatotic liver disease (MASLD) replaces nonalcoholic fatty liver disease (NAFLD). Model for end-stage liver disease (MELD) 3.0 replaced MELD-sodium. The prevalence of MASLD among adults is approximately 38%, and it is anticipated to rise by more than 55% by 2040. The economic burden in the USA related to MASLD exceeds $100 billion. If unrecognized, 20%-30% of adults with MASLD advance to MASH, cirrhosis of the liver, and may develop hepatocellular carcinoma. In the last 30 years, deaths related to cirrhosis have increased. As clinical approaches to screening are enhanced, the primary care physicians need to be indoctrinated. By recognizing risk factors, primary care providers can reduce the national disease burden and expedite interventions to improve patient outcomes. This manuscript aims to increase awareness of the availability of evolving knowledge necessary to minimize gatekeeping in the liver disease care path.   Cite this article as: Kalluru PKR, Onteddu N, Onteddu LPR, et al. From MASLD to MELD 3.0: integrating the spectrum of liver disease risk stratification into primary care. Eurasian J Med. 2026, 58(2), 1254, doi: 10.5152/eurasianjmed.2026.251254.

Identifiers

PMID41942414
PMCPMC13022925

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.