Evidence map›Paper›PMID 41942412›Full record

ArticleThe Eurasian journal of medicine2026

Evaluation of Diabetes Mellitus, Hyperlipidemia, and Thyroid Disease Comorbidities in Palmoplantar Pustulosis.

Ayşe Akbaş, Fadime Kılınç, Sertaç Şener, Yıldız Hayran

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Article in The Eurasian journal of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Ayşe AkbaşAnkara City Hospital, Dermatology, Ankara, Türkiye.
Fadime KılınçAnkara City Hospital, Dermatology, Ankara, Türkiye.
Sertaç ŞenerPrivate Clinic, Ankara, Türkiye.
Yıldız HayranAnkara City Hospital, Dermatology, Ankara, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPalmoplantar pustulosis (PPP) is a chronic, inflammatory pustular skin disease of unknown etiology. Genetic predisposition, smoking, focal infections, stress, and autoimmune diseases are implicated in its etiology. In this study, the presence of thyroid disease, diabetes mellitus (DM), and dyslipidemia in PPP was investigated based on comorbidities in psoriasis.

methodsThe records of 51 patients who were diagnosed with PPP both clinically and histopathologically and presented to the dermatology clinic were examined retrospectively. In these patients, fasting blood sugar, HbA1C, serum lipids (cholesterol, triglyceride, low-density lipoprotein (LDL), high-density lipoprotein (HDL)), thyroid-stimulating hormone (TSH), free thyroxine (ft4), free triiodothyronine (ft3), antithyroglobulin (antiTG), antithyroid peroxidase antibody (antiTPO) were recorded, and the presence of DM, dyslipidemia, and thyroid disease was investigated. Compared with the control group.

resultsThe average age of the patients was 47.9 (Å}12.1) years and the average disease duration was 5 (3-12) years. In the patients, hypertriglyceridemia was found in 29.4%, hypercholesterolemia in 45.1%, high LDL in 44%, low HDL in 14%, thyroid disease in 11.76%, and DM in 21.5%. When these values were compared with the control group, triglyceride values were significantly higher in the patients compared to the controls (P < .001).

conclusionsBased on the data of this study, as in psoriasis, it could be suggested that there is a possibility of DM, dyslipidemia, and thyroid disease comorbidity with PPP.   Cite this article as: Akbaş A, Kılın. F, Şener S, Hayran Y. Evaluation of diabetes mellitus, hyperlipidemia, and thyroid disease comorbidities in palmoplantar pustulosis. Eurasian J Med. 2026, 58(2), 1026, doi:10.5152/eurasianjmed.2026.251026.

Identifiers

PMID41942412
PMCPMC13022926

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.