ArticleAnnals of dermatology2026
Psychopathological Symptoms and Neuroticism in Female Outpatients With Dermatological Conditions: A Comparative Study.
Article in Annals of dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundDespite evidence suggesting a bidirectional relationship between psychological factors and skin disease, psychological distress and personality traits remain underexplored in dermatological care.
objectiveThis study aimed to compare psychopathological symptoms and personality traits between female outpatients with dermatological conditions and healthy controls.
methodsIn total, 159 outpatients with dermatological conditions and 160 healthy controls (all female) completed the Symptom Check List-90-Revised (SCL-90-R), and a shortened version of the NEO-Personality Inventory-Revised. Between-group comparisons were conducted using t-tests, and stepwise regression analysis was used to identify the psychopathological predictors of neuroticism.
resultsCompared with controls, the dermatology outpatient group demonstrated significantly higher SCL-90-R scores for all nine clinical scales and neuroticism, scoring lower in extraversion, openness, and agreeableness. Within the dermatology outpatient group, neuroticism was positively associated with all psychopathological dimensions (r=0.265-0.583;
conclusionFemale outpatients with dermatological conditions may experience considerable psychological distress and elevated neuroticism, even in the absence of clinical psychiatric diagnoses. Screening for psychological symptoms-including neuroticism, depression, somatization, and obsessive-compulsive features-should be considered in dermatological settings to better address patients' emotional well-being and optimize care outcomes.
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