ArticleContact dermatitis2026
Contact Sensitization in Patients With Frontal Fibrosing Alopecia: Patch Test Results With an Extended Baseline Series in Consecutive Patients.
Article in Contact dermatitis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionContact sensitization has been reported in patients with frontal fibrosing alopecia (FFA).
objectivesTo analyse sensitization in FFA-patients and the improvement of symptoms after allergen avoidance.
methodsWe performed patch tests with an extended baseline series in FFA-patients across Spain and assessed the allergen avoidance impact.
results133 FFA-patients were investigated. 97% were women. At least one positive allergen was found in 77/133 (58%). No differences were detected in the frequency of positive results compared with the population without FFA patch tested with an extended baseline series in the same period (52.3%) (p = 0.21). Having FFA was associated with being sensitized to propolis, shellac, and gallate mixture. Thirteen (9.8%) patients showed sensitization to salicylates, which was associated with subjective symptoms of intolerance to sunscreens or sun exposure. No evidence of clinical improvement was identified with allergen avoidance 4 months after patch testing.
conclusionNo sufficient evidence was found to justify routine patch testing in FFA patients, as no evidence of clinical improvement was identified by allergen avoidance and the relevance of FFA-associated sensitizations was largely uncertain. Patch testing with salicylates may be of interest in FFA-patients with subjective symptoms of intolerance to sun exposure or sunscreens.
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