Evidence map›Paper›PMID 41941643›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Hyperactive Rac converts sublethal to lethal trogocytosis in vivo.

Lauren Penfield, Abhinava K Mishra, Morgan Smith, Denise J Montell

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Danger at the border: Rac turns nibblers into murderers.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Lauren Penfield *Molecular, Cellular, and Developmental Biology Department, University of California, Santa Barbara, CA 93106.
Abhinava K Mishra *Molecular, Cellular, and Developmental Biology Department, University of California, Santa Barbara, CA 93106.ORCID 0000-0003-3733-3928
Morgan SmithMolecular, Cellular, and Developmental Biology Department, University of California, Santa Barbara, CA 93106.
Denise J MontellMolecular, Cellular, and Developmental Biology Department, University of California, Santa Barbara, CA 93106.ORCID 0000-0001-8924-5925

Funding

Spatiotemporal regulation of collective cell behaviors in Drosophila: Diversity Supplement for Predoctoral TrainingR01GM046425 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI MONTELL, DENISE J. · 1996 to 2025
$11.7M
American Cancer Society (ACS) PF-22-091-01-MMHHS | NIH (NIH) R01GM46425NIGMS NIH HHS R01 GM046425
6 · The paper itself

Abstract

The small GTPase Rac is an essential regulator of cell shape, migration, macropinocytosis, and phagocytosis. We found that expression of constitutively active Rac

Indexed as

Drosophila Proteinsrac GTP-Binding ProteinsAnimalsCell MovementDrosophila melanogasterFemaleMacrophagesMembrane ProteinsOvarian FollicleOvaryPhagocytosisDrosophila Proteinsdrpr protein, DrosophilaMembrane Proteinsrac GTP-Binding ProteinsCAR-MDrosophilaovaryphagocytosistrogocytosis

Identifiers

PMID41941643
PMCPMC13079925

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.