Evidence map›Paper›PMID 41941621›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Phage display-mediated immuno-PCR to detect low-abundance secreted proteins in

Myeonghoon Han, Baolong Xia, Ah-Ram Kim, Elizabeth Filine, Emily Stoneburner, Ting Miao, Ying Liu, Jonathan Zirin, Norbert Perrimon

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Phage display-mediated immuno-PCR to detect low-abundance secreted proteins inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Myeonghoon Han *Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
Baolong Xia *Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
Ah-Ram KimDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.ORCID 0000-0001-9597-6759
Elizabeth FilineDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
Emily StoneburnerDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
Ting MiaoDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
Ying LiuDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
Jonathan ZirinDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
Norbert PerrimonDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.ORCID 0000-0001-7542-472X

Funding

Functional genomics resources for the Drosophila - TR&D3P41GM132087 · NIGMS · HARVARD MEDICAL SCHOOL · PI MOHR, STEPHANIE E · 2019 to 2023
$6.8M
CANCAN - HarvardOT2CA278689 · NCI · HARVARD MEDICAL SCHOOL · PI NORBERT PERRIMON · 2022 to 2026
$1.1M
CANCAN ? CORNELLOT2CA278685 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI GONCALVES, MARCUS DASILVA · 2022 to 2023
$657k
Cancer Research UK (CRUK) CGCATF-2021/100022HHS | NIH | National Cancer Institute (NCI) 1 OT2 CA278685-01NCI NIH HHS OT2 CA278685NCI NIH HHS OT2 CA278689NIGMS NIH HHS P41 GM132087
6 · The paper itself

Abstract

Circulating hormones, that mediate communications across organs to maintain physiological balance, are commonly detected and quantified using enzyme-linked immunosorbent assays (ELISAs). However, while ELISA is well suited for organisms where sample blood can be readily obtained, its application is considerably more challenging in smaller organisms, particularly

Indexed as

Cell Surface Display TechniquesDrosophila melanogasterDrosophila ProteinsPolymerase Chain ReactionAnimalsEnzyme-Linked Immunosorbent AssayHemolymphPeptide LibraryDrosophila ProteinsPeptide Librarygene-editinghormoneimmuno-PCRinter-organ communicationsnanobody screen

Identifiers

PMID41941621
PMCPMC13079929

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.