Controlled Seeding of β-Amyloid Fibrillation Reveals Propagation of Structural Polymorphisms in Cellular Environments.

Tingyao Wang, Yan Sun, Yi Ran Lin, Lan Yao, Wei Qiang

Abstract read

In one paragraph

Article in Biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tingyao WangDepartment of Chemistry, Binghamton University, The State University of New York, Vestal, New York 13850, United States.

Yan SunSmall Scale System Integration and Packaging (S3IP), Binghamton University, Vestal, New York 13850, United States.

Yi Ran LinDepartment of Chemistry, Binghamton University, The State University of New York, Vestal, New York 13850, United States.

Lan YaoSmall Scale System Integration and Packaging (S3IP), Binghamton University, Vestal, New York 13850, United States.

Wei QiangDepartment of Chemistry, Binghamton University, The State University of New York, Vestal, New York 13850, United States.ORCID 0000-0002-0044-810X

Funding

Molecular Structural Basis of Non-specific Neuronal Membrane Disruption Induced by Early-Stage Beta-Amyloid Peptide AggregationR01GM125853 · NIGMS · STATE UNIVERSITY OF NY,BINGHAMTON · PI Wei Qiang · 2018 to 2026

$2.5M

NIGMS NIH HHS R01 GM125853

6 · The paper itself

Abstract

Molecular-level structural polymorphisms of β-amyloid (Aβ) aggregates in Alzheimer's disease patients are pathologically important. However, tracking the propagation and modulation of Aβ structural polymorphisms via

Indexed as

Amyloid beta-PeptidesPeptide FragmentsAlzheimer DiseaseAmyloidHumansNuclear Magnetic Resonance, BiomolecularAmyloidAmyloid beta-PeptidesPeptide Fragments

Identifiers

PMID41941608

DOI10.1021/acs.biochem.6c00013

PMCPMC13104022

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.