Evidence map›Paper›PMID 41941551›Full record

ArticleCirculation2026

Response by Stepanian and Jaffe to Letters Regarding Article, "Ponatinib, but Not the New Abl-Kinase Inhibitor Asciminib, Activates Platelets, Leukocytes, and Endothelial Cell TNF Signaling to Induce Atherosclerotic Plaque Inflammation, Myocardial Infarction, and Stroke".

Alec Stepanian, Iris Z Jaffe

Abstract readLetter
In one paragraph

Article in Circulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alec StepanianMolecular Cardiology Research Institute, Tufts Medical Center, Boston, MA. Graduate School of Biomedical Sciences, Tufts School of Medicine, Boston, MA.ORCID 0000-0003-4719-5792
Iris Z JaffeMolecular Cardiology Research Institute, Tufts Medical Center, Boston, MA. Graduate School of Biomedical Sciences, Tufts School of Medicine, Boston, MA.ORCID 0000-0001-9300-1253

Funding

Novel strategies to understand, predict, and prevent vascular toxicity of targeted CML therapiesR01HL155078 · NHLBI · TUFTS MEDICAL CENTER · PI JAFFE, IRIS Z · 2021 to 2024
$2.6M
NHLBI NIH HHS R01 HL155078
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41941551
PMCPMC13488980

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.