Evidence map›Paper›PMID 41941455›Full record

ReviewPLoS neglected tropical diseases2026

Household and community-based approaches to malaria and cholera prevention: A narrative review with case studies from Uganda and Mozambique.

Giacomo Guido, Valentina Totaro, Peter Lochoro, Jerry Ictho, Edoardo Occa, Kajal Chhaganlal, Francesco Vladimiro Segala, Giovanni Dall'Oglio, Braunde Francisco Mechendura, Elmano Gomonda and 10 more

Abstract readReview
In one paragraph

Review in PLoS neglected tropical diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Giacomo GuidoClinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari, Italy.
Valentina TotaroClinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari, Italy.ORCID https://orcid.org/0009-0004-5157-6787
Peter LochoroDoctors with Africa, CUAMM, Kampala, Uganda.
Jerry IcthoDoctors with Africa, CUAMM, Kampala, Uganda.
Edoardo OccaOperational Research Unit, Doctors with Africa CUAMM, Padua, Italy.
Kajal ChhaganlalDepartment of Research, Faculty of Health Sciences, Universidade Catolica de Mocambique, Beira, Mozambique.
Francesco Vladimiro SegalaClinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari, Italy.
Giovanni Dall'OglioDoctors with Africa, CUAMM, Kampala, Uganda.
Braunde Francisco MechenduraSaude familiar e comunitaria, Curso de Medicina Geral, Faculdade de Ciencias de Saude da Universidae Catolica de Mocambique, Beira, Mozambique.
Elmano GomondaDepartment of Research, Faculty of Health Sciences, Universidade Catolica de Mocambique, Beira, Mozambique.
Giovanni PutotoOperational Research Unit, Doctors with Africa CUAMM, Padua, Italy.
Federica PencoOperational Research Unit, Doctors with Africa CUAMM, Padua, Italy.
Muhammad AsaduzzamanDepartment of Community Medicine and Global Health, Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway.
Emanuele NicastriHigh Intensity Care Infectious Diseases, National Institute for Infectious Diseases 'Lazzaro Spallanzani' IRCCS, Rome, Italy.
Ferenc Balázs FarkasInstitute of Medical Microbiology, Faculty of Medicine, Semmelweis University, Budapest, HungaryPediatric Center, Semmelweis University, Budapest, Hungary.
Roberta IattaInterdisciplinary Department of Medicine, University of Bari, Bari, Italy.
Botond LakatosDepartment of Internal Medicine and Hematology, Departmental Group of Infectious Diseases, Semmelweis University, Budapest, Hungary.
Raja Waqar AliClinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari, Italy.
Annalisa SaracinoClinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari, Italy.
Francesco Di GennaroClinic of Infectious Diseases, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari, Bari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHousing conditions play a fundamental role in infectious diseases transmission, particularly in endemic regions. Structural modifications to homes-such as screened windows and doors, sealed eaves, elevated flooring, and insecticide-treated barriers-are increasingly recognized as key strategies for reducing mosquito entry and, consequently, malaria risk. Similarly, improved latrine, proper waste disposal, and the possibility to hand wash can help to reduce the spread of waterborne diseases such as cholera. However, their effectiveness and feasibility vary across geographical and socio-economic settings. This study examines the impact of housing-based interventions on malaria and cholera prevention through two case studies conducted in Uganda and Mozambique.

methodsA literature review was conducted alongside case studies from Uganda and Mozambique, where housing interventions for endemic infectious diseases prevention have been implemented. Data were collected from scientific literature, local health reports, and field observations.

resultsThe combination of multiple preventive measures at the community level, including both structural modifications to housing and changes in domestic behavior, holds great potential in combating various endemic diseases in low-income countries, such as malaria and cholera. These integrated strategies are generally low-cost, community-acceptable, and easily implementable, and can complement existing large-scale control programs.

conclusionHouse-based interventions represent a sustainable and complementary strategy for malaria and cholera control in endemic regions. However, their successful implementation depends on affordability, cultural adaptation, and integration with existing control programs. Future research should focus on scaling up these interventions and evaluating their long-term impact on vector- and water-borne diseases transmission in endemic and low-resource settings.

Indexed as

CholeraHousingMalariaFamily CharacteristicsHumansMozambiqueUganda

Identifiers

PMID41941455
PMCPMC13068327

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.