Evidence map›Paper›PMID 41940838›Full record

ArticleEchocardiography (Mount Kisco, N.Y.)2026

Added Value of Rotational Mechanics to Longitudinal Indices in the Risk Stratification of Patients With Left Ventricular Hypertrophy.

Juan Geraldo, Celia Gil, Alejandro Queipo, Guillermo García-Martín, Ester Galiana, Alberto Hidalgo, Paula Gramage, Hector Martinez-Navarro, Jorge Lowenstein, Ildefonso Roldán and 1 more

Abstract read
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Article in Echocardiography (Mount Kisco, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Juan GeraldoDepartment of Cardiology, Hospital Universitario Doctor Peset, Valencia, Spain.
Celia GilDepartment of Cardiology, Hospital Universitario Doctor Peset, Valencia, Spain.
Alejandro QueipoDepartment of Cardiology, Hospital Universitario Doctor Peset, Valencia, Spain.
Guillermo García-MartínDepartment of Cardiology, Hospital Universitario Doctor Peset, Valencia, Spain.
Ester GalianaDepartment of Cardiology, Hospital Universitario Doctor Peset, Valencia, Spain.
Alberto HidalgoDepartment of Cardiology, Hospital Universitario Doctor Peset, Valencia, Spain.
Paula GramageDepartment of Cardiology, Hospital Universitario Doctor Peset, Valencia, Spain.
Hector Martinez-NavarroCoMMLab, Departament d'Informatica, Universitat de Valencia, Valencia, Spain.
Jorge LowensteinCardiodiagnosis Department, Medical Research, Buenos Aires, Argentina.
Ildefonso RoldánDepartment of Cardiology, Hospital Universitario Doctor Peset, Valencia, Spain.
Vicente MoraDepartment of Cardiology, Hospital Universitario Doctor Peset, Valencia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn the past, analysis of the rotational mechanics of the left ventricle (LV) has been complicated by a confusing codification system and also because it has been approached independently from myocardial function state. We hypothesized that, once global longitudinal strain (GLS) is altered as early sign of myocardial involvement, rotational mechanics is a determining factor in LV ejection fraction (LVEF) in patients with LV hypertrophy (LVH).

methods2D-speckle tracking echocardiographic images were used to generate GLS and rotational parameters. Myocardial dysfunction was defined by GLS < 16%. We calculated the "Rotational Gradient" (RG), which is the result of the interaction of basal and apical rotations, whether twist (positive RG value) or rigid rotation pattern (negative RG value). The study included 67 healthy controls and 348 patients with LVH (173 with GLS

resultsUnlike patients with GLS

conclusionsRotational mechanics should be interpreted based on myocardial function state. In patients with GLS < 16% a smaller RG is associated with lower LVEF. RG can be used to stratify patients with LVH at risk of heart failure.

Indexed as

EchocardiographyHeart VentriclesHypertrophy, Left VentricularFemaleGlobal Longitudinal StrainHumansMaleMiddle AgedReproducibility of ResultsRisk AssessmentSensitivity and SpecificityStroke Volumeleft ventricular hypertrophylongitudinal strainmyocardial functionrotational gradientrotational mechanicsspeckle tracking echocardiography

Identifiers

PMID41940838
PMCPMC13052374

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.