Evidence map›Paper›PMID 41940815›Full record

ArticleAntimicrobial agents and chemotherapy2026

Ceftazidime-avibactam resistance evolution in

Ava J Dorazio, Ellen G Kline, Kevin M Squires, Sunish Shah, Daria Van Tyne, Janet Y Wu, Jason M Pogue, Ryan K Shields

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ava J DorazioDepartment of Medicine, Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0009-0007-8148-8835
Ellen G KlineDepartment of Medicine, Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0009-0006-7167-6368
Kevin M SquiresDepartment of Medicine, Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Sunish ShahAntibiotic Management Program, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Daria Van TyneDepartment of Medicine, Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-7284-0103
Janet Y WuDepartment of Pharmacy, Cleveland Clinic, Cleveland, Ohio, USA.
Jason M PogueCollege of Pharmacy, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0003-4780-6215
Ryan K ShieldsDepartment of Medicine, Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-9794-5665

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Twelve pairs of baseline and post-exposure

Indexed as

Anti-Bacterial AgentsAzabicyclo Compoundsbeta-LactamsCeftazidimePseudomonas aeruginosaAmino Acid SubstitutionBacterial Outer Membrane ProteinsBacterial Proteinsbeta-LactamasesCefepimeCefiderocolCephalosporinsCyclooctanesDrug CombinationsDrug Resistance, Multiple, BacterialHumansAmpC beta-lactamasesAnti-Bacterial Agentsavibactam, ceftazidime drug combinationAzabicyclo CompoundsBacterial Outer Membrane ProteinsBacterial Proteinsbeta-Lactamasesbeta-LactamsCefepimecefepime-zidebactamCefiderocolCeftazidimeceftolozane, tazobactam drug combinationCephalosporinsCyclooctanesDrug CombinationsImipenemMembrane Transport ProteinsMexA protein, Pseudomonas aeruginosaMexB protein, Pseudomonas aeruginosaOprM protein, Pseudomonas aeruginosaPenicillanic AcidPiperidinesrelebactamTazobactamAmpCcefepime-zidebactamceftazidime-avibactamceftolozane-tazobactamMexAB-OprM efflux systemβ-lactam cross-resistance

Identifiers

PMID41940815
PMCPMC13148059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.